Sökning: "telomere length"
Visar resultat 1 - 5 av 46 avhandlingar innehållade orden telomere length.
1. Telomere length : dynamics and role as a biological marker in malignancy
Sammanfattning : Telomeres are protective structures at the end of our chromosomes, composed of multiple repeats of the DNA sequence TTAGGG. They are essential for maintaining chromosomal stability by preventing damage and degradation of the chromosome ends. LÄS MER
2. What modulates telomere dynamics? : Inheritance, developmental effects, and physiological challenges
Sammanfattning : Telomeres are the conservative sequence repeats located at the end of linear chromosomes that have been the focus of intensive research across many disciplines over the last four decades. They function as a cap to protect the chromosome ends from fusion to other chromosomes and to prevent chromosome degradation. LÄS MER
3. Exposure, telomere length, and cancer risk
Sammanfattning : Telomeres are tandem repeats of TTAGGG at the end of eukaryotic chromosomes. Telomeres play a key role in chromosome stability and regulation of the cellular lifespan. Telomeres are shortened during cell division, and probably, by not yet well characterised factors in the environment. LÄS MER
4. LIVING WITH PARASITES: AVIAN MALARIA, TELOMERE LENGTH AND LIFE HISTORY TRADE-OFFS
Sammanfattning : Haemosporidia is a well-studied group of parasites, which infect mammals, reptiles and birds and use blood sucking vectors for their transmission. By conducting natural population studies and experimental infections, We have been able to detect and quantify Haemosporidia from avian blood to investigate how these pathogens affect their avian hosts. LÄS MER
5. Telomere length - inheritance pattern and role as a biomarker
Sammanfattning : Telomeres are repetitive TTAGGG structures ending each chromosome and thereby protecting its integrity. Due to the end-replication problem, telomeres shorten with each cell division. When reaching a critical telomere length (TL), the cells stop dividing and enter replicative senescence. LÄS MER