Sökning: "cell degranulation"

Visar resultat 21 - 25 av 72 avhandlingar innehållade orden cell degranulation.

  1. 21. Imaging and Spectroscopic Mapping of Blood Cell Activity : Nanoparticles and Neutrophil Extracellular Traps

    Författare :Kalle Bunnfors; Kajsa Uvdal; Caroline Brommesson; Christelle Prinz; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Neutrophils; Neutrophil extracellular traps; fluorescence; XPS; TEM;

    Sammanfattning : Imaging and visualization of cell activity when exposed to nanomaterial are of main importance, when investigating biological response to a wide range of biomaterials from medical implants to smart nanoprobes. The ability to provide molecular and chemical information with spatial resolution in the region of sub-µm leads to increased insight and understanding of these biological challenges. LÄS MER

  3. 22. Triggering and mechanisms of natural killer cell mediated cytotoxicity

    Författare :Yenan Bryceson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Natural killer cells; antibody dependent cellular cytotoxicity; natural cytotoxicity; immunodeficiency; hemophagocytic lymphohistiocytosis;

    Sammanfattning : Natural killer (NK) cells are innate immune cells that contribute to defense against infected and transformed cells by target cell killing and cytokine release. In addition, data suggest that NK cells contribute to immune homeostasis and reproduction. LÄS MER

  4. 23. T cell subsets and disease mechanisms in inflammatory myopathies

    Författare :Jayesh Pandya; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The idiopathic inflammatory myopathies (IIMs) are a heterogeneous group of chronic muscle disorders, typically displaying infiltrating T cells in skeletal muscle tissue and classified into polymyositis, dermatomyositis and sporadic inclusion body myositis. Several studies involving both humans and animal models point towards a role for T cells in the pathogenesis of IIMs, however, the precise phenotype, functionality and specificity of pathogenic T cells remain elusive. LÄS MER

  5. 24. Developing otitis media : experimental studies in particular regarding inflammatory changes in the tympanic membrane

    Författare :Per Olof Eriksson; Sten Hellström; Karin Prellner; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Otorhinolaryngology; otitis media with effusion; acute otitis media; myringotomy; tympanic membrane; rat; Streptococcus pneumoniae; compound 48 80; mast cell; Otorhinolaryngologi; Otorhinolaryngology; Otorhinolaryngologi; Oto-Rhino-Laryngology; oto-rhino-laryngologi;

    Sammanfattning : Otitis media (OM), one of the commonest of childhood diseases, causes much suffering. OM exists in a variety of forms, two of which are acute otitis media (AOM) and otitis media with effusion (OME). LÄS MER

  7. 25. Alpha 1-antitrypsin: A Role in Cancer Progression

    Författare :Inga Zelvyté; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer; onkologi; Cytologi; cancerology; oncology; Cytology; invasion; neutrophils; cancer cell; Alpha1- antitrypsin; proteinase inhibitors;

    Sammanfattning : Alpha1-antitrypsin (AAT), a circulating single-chain glycoprotein is the most abundant serine proteinase inhibitor in human plasma. AAT is an acute phase protein, its levels increase rapidly to concentrations exceeding 50mM in response to inflammation, infection and malignant diseases. LÄS MER