Sökning: "natural cytotoxicity"
Visar resultat 1 - 5 av 118 avhandlingar innehållade orden natural cytotoxicity.
1. Biologically Interesting Compounds from Natural Sources
Sammanfattning : Natural products have traditionally played a major role in the drug discovery process. Besides constituting extremely popular drugs in the market, and an ever-increasing source of interesting and novel chemical structures, they have also aided the characterization of many a pharmacological target. LÄS MER
2. Mechanisms regulating Natural Killer Cell Cytotoxicity
Sammanfattning : Over the last 50 years, cancer survival rates have steadily improved thanks to earlier detection and novel treatment regimens. For example, drugs that act on the immune system, so-called immunotherapy, have drastically increased the prospect of survival for patients suffering from some of the most aggressive cancer types including advanced malignant melanoma. LÄS MER
3. Structural studies of heterogeneous amyloid species of lysozymes and de novo protein albebetin and their cytotoxicity
Sammanfattning : A number of diseases are linked to protein folding problems which lead to the deposition of insoluble protein plaques in the brain or other organs. These diseases include prion diseases such as Creutzfeld-Jakob disease, Alzheimer's disease, Parkinson's disease and type II (non-insulin dependent) diabetes. LÄS MER
4. Antiparasitic metabolites from plants used in the Tacana Bolivian native tribe : Traditional medicine, an overview of natural products with medicinal interest
Sammanfattning : The thesis aims to contribute to the preservation of traditional medicinal knowledge of the Tacana Bolivian native tribe, as well as to the isolation and characterization of antiparasitic metabolites from plants used for the treatment of endemic diseases. A selection of medicinal plants, made in collaboration with the Tacana communities who decided which plants have a specific medicinal propose, were collected and identified by the national herbarium of Bolivia, and confirmed by healers from the most representative communities. LÄS MER
5. Synthesis of Bioactive Analogues of Marasmane Dialdehydes
Sammanfattning : The modification of drugs into pro-drugs is an attractive concept allowing you to tweak the chemical and physical properties of a drug without changing the original structure of the active compound. In principle, any compound possessing a preferred biological activity can be transformed into a pro-drug. LÄS MER
