Sökning: "cell degranulation"

Visar resultat 11 - 15 av 72 avhandlingar innehållade orden cell degranulation.

  1. 11. NO Effect on Inflammatory Reaction in Extracorporeal Circulation : Ex vivo Studies

    Författare :Mika Lahtinen; Jan Borowiec; Per Venge; Vibeke Videm; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; Cardiac surgery; extracorporeal circulation; inflammatory reaction; NO; degranulation; neutrophil; eosinophil; basophil; complement; contact system; coagulation; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin; Clinical Chemistry; klinisk kemi;

    Sammanfattning : Nitric oxide (NO) is expressed in inflammatory tissues. However, NO effects are controversial in inflammation; NO is described as acting in a dose dependent manner and possess both pro-inflammatory and anti-inflammatory properties. LÄS MER

  3. 12. Identification of galectins as novel inflammatory mediators

    Författare :Jenny Almkvist; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Human neutrophils; NADPH-oxidase; Galectin-1; Galectin-3; priming; degranulation;

    Sammanfattning : The human neutrophils play important roles in the host defence against invading microorganisms. To eliminate bacteria or other invaders the neutrophils have to leave the bloodstream and cross the endothelium, migrate through the extracellular matrix towards the site of infection and phagocytose the prey to ultimately kill it. LÄS MER

  4. 13. Harnessing the immunoregulatory capacity of single-stranded oligonucleotides to modulate innate immunity

    Författare :Aleksandra Dondalska; Anna-Lena Spetz; Jenny Hallgren Martinsson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; single-stranded oligonucleotides; Toll-like receptors; influenza; respiratory syncytial virus; dendritic cell; mast cell; virus infection; inflammation; itch; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : As the first line of defense, the innate immune system is exceptionally efficacious against invading pathogens but must be tightly regulated to avoid immune-related pathogenesis. Accordingly, the innate immune system recognizes highly conserved components associated with infections and damaged cells using a limited number of pattern-recognition receptors (PRRs), which are differentially expressed across cell types. LÄS MER

  5. 14. Mast cells: bad enemies or good friends? : A study of the effects of IgG immune complexes on mast cell biology

    Författare :Lisa M Larsson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mast cell; Fc receptor; Apoptosis; Immune complex; Adjuvant; CTA1-DD.;

    Sammanfattning : Mast cells are classically defined as bad enemies to human health due to their critical involvement in IgE-dependent allergy by virtue of the expression of the high affinity IgE receptor, FcgammaRI, on these cells. However, mouse mast cells also express FcgammaRIIB and FcgammaRIIIA, two receptors that bind IgG especially in the form of IgG immune complexes. LÄS MER

  7. 15. Mast cell responses to danger signals

    Författare :Mattias Enoksson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Detecting and responding to danger is a paramount function of the immune system. Compounds heralding danger can be divided into two groups: exogenous and endogenous danger signals. LÄS MER