Sökning: "compound 48 80"
Visar resultat 1 - 5 av 16 avhandlingar innehållade orden compound 48 80.
1. Peripheral Regulation of Pain and Itch
Sammanfattning : Pain and itch are diverse sensory modalities, transmitted by the somatosensory nervous system. Stimuli such as heat, cold, mechanical pain and itch can be transmitted by different neuronal populations, which show considerable overlap with regards to sensory activation. LÄS MER
2. Developing otitis media : experimental studies in particular regarding inflammatory changes in the tympanic membrane
Sammanfattning : Otitis media (OM), one of the commonest of childhood diseases, causes much suffering. OM exists in a variety of forms, two of which are acute otitis media (AOM) and otitis media with effusion (OME). LÄS MER
3. Pharmacology of Palmitoylethanolamide and Related Compounds
Sammanfattning : Anandamide (AEA) is an endogenous fatty acid which activates the same cannabinoid receptors as ∆9-tetrahydrocannabinol, the psychoactive substance in marijuana. In vivo, anandamide exerts a number of actions including effects upon pain and inflammation. LÄS MER
4. Role of mast cell-derived mediators for leukocyte / endothelium-interactions and microvascular mechanisms in inflammation and in anaphylaxis
Sammanfattning : The overall objective of this thesis was to study the roles of mast cell-derived mediators for leukocyte/endothelium interactions and microvascular mechanisms in inflammation and in anaphylaxis, using mast cell-deficient Ws/Ws rats and their wild-type +/+ littermates. The efflux of endogenous histamine and edema formation evoked by subplantar injection of compound 48/80 in rat hind-paws was dose-dependent in +/+ rats, and was essentially lacking in Ws/Ws rats. LÄS MER
5. Non-digestible Polysaccharides and Intestinal Barrier Function : specific focus on its efficacy in elderly and patients with Crohn’s disease
Sammanfattning : A large number of elderly suffer from gastrointestinal (GI) symptoms such as constipation and diarrhoea. The underlying mechanisms of age-acquired GI symptoms are not well studied but are necessary to clarify in order to recommend the right treatment. LÄS MER