Sökning: "blood sample"

Visar resultat 31 - 35 av 343 avhandlingar innehållade orden blood sample.

1. 31. Novel microfluidic based sample preparation methods for rapid separation and detection of viable bacteria from blood for sepsis diagnostics

   Författare :Sharath Narayana Iyengar; Aman Russom; Jonas Tegenfeldt; KTH; []
   Nyckelord :microfluidics; Bioteknologi; Biotechnology;

   Sammanfattning : Sepsis is a serious medical condition characterized by a whole-body inflammatory response caused by bloodstream infection. The final stage of sepsis can lead to septic shock, multiple organ failure, and death. In early sepsis, the concentration of bacteria in the bloodstream is typically low, making diagnosis challenging. LÄS MER

3. 32. Health symptoms and potential effects on the blood-brain and blood-cerebrospinal fluid barriers associated with use of wireless telephones

   Författare :Fredrik Söderqvist; Lennart Hardell; David Carpenter; Örebro universitet; []
   Nyckelord :radiofrequency fields; mobile telephone; DECT-telephone; cordless telephone; children; adolescents; well-being; choroid plexus; biomarkers; S100B; transthyretin; MEDICINE; MEDICIN; Medicine; Medicin;

   Sammanfattning : Recent years have seen a rapid increase in the use of wireless telephones, yet little systematic data exist on the actual use of such devices in the general population. Mobile and cordless telephones emit radiofrequency fields (RF) raising concern about possible adverse health effects. LÄS MER

4. 33. Factors influencing the risk of diabetic nephropathy : analyses of genes, smoking and diet

   Författare :Anna Möllsten; Gisela Dahlquist; Lise Tarnow; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; type 1 diabetes; diabetic nephropathy; oxidative stress; smoking; diet; blood pressure; renin-angiotensin system; nitric oxide synthase; Kidney diseases; Njursjukdomar;

   Sammanfattning : Diabetic long-term complications, despite intensive treatment, cause serious handicaps at relatively young age in diabetic patients. Diabetic nephropathy (DN) develops in up to 30% of patients with type 1 diabetes (T1D). LÄS MER

5. 34. Prevention of hemolysis as a novel strategy to limit hemoglobin-mediated lipid oxidation in fish - towards a more sustainable use of fish raw materials

   Författare :Semhar Ghirmai; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; hemoglobin; herring Clupea harengus ; fish; rainbow trout Oncorhynchus mykiss ; erythrocyte; hemolysis; side-stream; antioxidant; lipid oxidation; blood plasma;

   Sammanfattning : Hemoglobin (Hb) has been recognized as a main pro-oxidant in fish, causing fast and intense lipid oxidation. This thesis explores the hypothesis that maintaining red blood cells (RBCs) intact for an extended time during fish processing could delay Hb-mediated lipid oxidation. LÄS MER

7. 35. Metabolomics, body composition and fracture

   Författare :Rui Zheng; Karl Michaëlsson; Harri Sievänen; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Metabolomics; LC-MS; sample quality; cohort; body composition; fracture; Medicinsk vetenskap; Medical Science; Bioinformatics; Bioinformatik; Epidemiologi; Epidemiology; Orthopaedics; Ortopedi; Kemi med inriktning mot analytisk kemi; Chemistry with specialization in Analytical Chemistry;

   Sammanfattning : In this thesis, I evaluated the impact of pre-centrifugation sample management on the plasma metabolome, providing verification for the protocol used in a study where I applied metabolomics to better understand the role of body composition in fracture occurrence using a large population-based cohort.  In paper 1, I applied untargeted liquid chromatography-mass spectrometry (LC-MS) metabolomics analysis to plasma samples (n = 471) from healthy donors to predict and evaluate the effect of pre-centrifugation temperature and delay time on metabolomics data using a combination of random forest and generalized linear models. LÄS MER