Sökning: "bacterial receptor"

Visar resultat 16 - 20 av 193 avhandlingar innehållade orden bacterial receptor.

  1. 16. Macrophage programming and host responses to bacterial infection

    Författare :Xiao Wang; Hong Sjölinder; Martin Rottenberg; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Macrophages; meningococci; mycobacteria; NhhA; CD46; cytokines; molekylärgenetik; Molecular Genetics;

    Sammanfattning : Macrophages are dynamic, plastic, and heterogeneous immune cells that play an important role in host immune defense against bacterial infection. Various bacterial pathogens, such as Neisseria meningitidis and Mycobacterium tuberculosis, can modulate host immune responses by interfering with macrophage differentiation and polarization. LÄS MER

  3. 17. Bacterial display systems for engineering of affinity proteins

    Författare :Filippa Fleetwood; John Löfblom; Harald Kolmar; KTH; []
    Nyckelord :Combinatorial protein engineering; staphylococcal display; Affibody; biparatopic; VEGFR2; nanobody; E. coli display; autotransporter; Bioteknologi; Biotechnology;

    Sammanfattning : Directed evolution is a powerful method for engineering of specific affinity proteins such as antibodies and alternative scaffold proteins. For selections from combinatorial protein libraries, robust and high-throughput selection platforms are needed. LÄS MER

  4. 18. Experimental bacterial meningitis : studies on immunopathogenesis and immunoregulation

    Författare :Asim Eltayeb Diab; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Bacterial meningitis is an inflammatory disease of the central nervous system (CNS) which occurs when bacteria gain entry to the subarachnoid space (SAS). Bacterial replication or Iysis leads to the exposure of cell components. LÄS MER

  5. 19. Receptor Interactions Between Pathogenic Bacteria and Host Cells

    Författare :Lena Lövkvist; Ann-Beth Jonsson; Heiko Herwald; Uppsala universitet; []
    Nyckelord :Microbiology; Type IV pili; Lipooligosaccharide; ScpC protease; CD46; Mikrobiologi;

    Sammanfattning : This thesis focuses on host and pathogen specific interactions during invasive disease. We have investigated the role and impact of different virulence factors of Neisseria gonorrhoeae, N. meningitidis and Streptococcus pyogenes on host epithelial cells and in vivo. N. LÄS MER

  7. 20. B cell activation in vitro: thymus-dependent immune responses and bacterial cell surface proteins

    Författare :Karol Axcrona; Immunologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nuclear transport; bacterial Ig-binding proteins; CD40L promoter; CD21; Ig; B lymphocyte activation in vitro; CD40; Immunology; serology; transplantation; Immunologi; serologi;

    Sammanfattning : In this thesis aspects of peripheral B lymphocyte differentiation were studied. Through in vitro experiments, B lymphocyte activation was assessed. B lymphocytes express immunoglobulin (Ig) specific for a certain antigen on the cell surface, and when surface Ig is crosslinked by an antigen, the cell is activated. LÄS MER