Sökning: "VEGFR2"

Visar resultat 1 - 5 av 35 avhandlingar innehållade ordet VEGFR2.

  1. 1. Regulation of VEGFR2 signaling in angiogenesis and vascular permeability

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Chiara Testini; Uppsala universitet.; [2016]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; VEGFR2; angiogenesis; permeability; NRP1; Y949; Y1212; paladin; Molekylär medicin; Molecular Medicine;

    Sammanfattning : Angiogenesis and vascular permeability occur in physiological and pathological conditions. Angiogenesis denotes the process of blood vessel formation from preexisting quiescent vessels. LÄS MER

  2. 2. Neuropilin-1 regulation of tumor vascularization and growth

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Eric Morin; Uppsala universitet.; [2018]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Angiogenesis; Neuropilin-1; VEGFR2; tumor biology; pancreatic ductal adenocarcinoma; renal cell carcinoma; Medical Cell Biology; Medicinsk cellbiologi;

    Sammanfattning : Angiogenesis, the formation of new blood vessels from existing ones, is dysregulated during tumor progression as a result of chronic hypoxia and inflammation. Such alterations lead to a lack of vessel hierarchy, and the formation of poorly perfused, leaky and blunt-ended vessels, contributing to disease progression. LÄS MER

  3. 3. Bacterial display systems for engineering of affinity proteins

    Detta är en avhandling från Stockholm : KTH Royal Institute of Technology

    Författare :Filippa Fleetwood; KTH.; [2014]
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Combinatorial protein engineering; staphylococcal display; Affibody; biparatopic; VEGFR2; nanobody; E. coli display; autotransporter; Biotechnology; Bioteknologi;

    Sammanfattning : Directed evolution is a powerful method for engineering of specific affinity proteins such as antibodies and alternative scaffold proteins. For selections from combinatorial protein libraries, robust and high-throughput selection platforms are needed. LÄS MER

  4. 4. Exploring Cellular Dynamics From Vesicle Tethering to Cell Migration

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Parham Ashrafzadeh; Uppsala universitet.; [2016]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; angiogenesis; cancer; cell migration; exocyst complex; exocytosis; FGD5; lipid rafts; plasma membrane; receptor trafficking; VEGFR2;

    Sammanfattning : Cells in the body communicate with each other in order to cooperate efficiently. This communication is in part achieved by regulated secretion of signaling molecules, which when released from a cell may activate receptors present at the plasma membrane of an adjacent cell. Such signals affect both cell fate and behavior. LÄS MER

  5. 5. Biological consequences of endothelial cell signaling

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Ross Smith; Uppsala universitet.; [2018]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; VEGFR2; Mechanosensing; Retinopathy; Biologi; Biology;

    Sammanfattning : Endothelial cells make up the inner lining of blood and lymphatic vessels, where they participate in functions vital to survival of the tissue; endothelial cells maintain vessel integrity, dynamically respond to the changing metabolic needs of tissues, and participate in many tissue-specific functions. Endothelial cells sense environmental cues which initiate signal transduction pathways that regulate behavior. LÄS MER