Sökning: "arrhythmia"

Visar resultat 11 - 15 av 94 avhandlingar innehållade ordet arrhythmia.

  1. 11. Teratogenicity as a consequence of drug-induced embryonic cardiac arrhythmia : Common mechanism for almokalant, sotalol, cisapride, and phenytoin via inhibition of IKr

    Författare :Anna-Carin Sköld; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biosciences; IKr; delayed rectifying K channel; embryonic cardiac arrhythmia; teratogenicity; Farmaceutisk biovetenskap; Biopharmacy; Biofarmaci; Toxicology; toxikologi;

    Sammanfattning : During the last years, drugs that prolong the repolarisation phase of the myocardial action potential, due to inhibition of the rapid component of the delayed-rectifying potassium channel (IKr) have been in focus. In addition to arrhythmogenic potential, selective Ikr-blockers have also been shown to be embryotoxic and teratogenic in animal studies. LÄS MER

  3. 12. Respiratory Sinus Arrhythmia and Emotion : Effects of pictorial stimuli and state anxiety

    Författare :Peter Jönsson; Institutionen för psykologi; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Psychology; state anxiety; emotion; HRV; heart rate variability; RSA; Respiratory sinus arrhythmia; Psykologi;

    Sammanfattning : Respiratory sinus arrhythmia (RSA) refers to heart rate variations due to respiration, which results from parasympathetic nervous system activity mediated via the tenth cranial nerve, the vagus. Thus, the magnitude of RSA is considered as an index of cardiac vagal tone. This thesis explored RSA during emotional responding in healthy women and men. LÄS MER

  4. 13. Outcomes and safety of new techniques for pulmonary vein isolation in patients with paroxysmal and persistent atrial fibrillation : A study based on randomised trials and registries

    Författare :David Mörtsell; Carina Blomström-Lundqvist; Stefan Lönnerholm; Isabel Deisenhofer; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; atrial fibrillation; antiarrhythmic drugs; ablation; cryoballoon; radiofrequency; pulmonary vein isolation; quality of life; arrhythmia monitoring; implantable cardiac monitor; atrial fibrillation burden; health economics; Cardiology; Kardiologi;

    Sammanfattning : Atrial fibrillation (AF) is a common disease with a high prevalence in the adult population. Treatment of AF encompasses antiarrhythmic drugs and catheter ablation to reduce symptoms. LÄS MER

  5. 14. Long QT syndrome in Sweden : founder effects and associated cardiac phenotypes

    Författare :Annika Winbo; Annika Rydberg; Eric Schulze-Bahr; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Long QT Syndrome; Jervell and Lange-Nielsen Syndrome; inherited arrhythmia; founder effects; clinical genetics; haplotype analysis; mutation age; founder mutation; clinical phenotype; life-threatening cardiac events; mutation-specific; KCNQ1 gene; modifier genes; sequence variants; risk stratification; risk factor; gender; pediatrik; Pediatrics;

    Sammanfattning : Background: We aimed to increase the knowledge regarding the familial arrhythmogenic disorder Long QT Syndrome (LQTS) and its recessive variant Jervell and Lange-Nielsen Syndrome (JLNS) in Sweden, including prevalences and clinical phenotypes. A specific focus was directed towards two KCNQ1 mutations –p.Y111C and p. LÄS MER

  7. 15. Arrhythmogenic Right Ventricular Cardiomyopathy : Genetic and Electrocardiographic Aspects on Risk of Ventricular Arrhythmia and Diagnosis

    Författare :Anneli Svensson; Cecilia Gunnarsson; Pyotr Platonov; Lars O. Karlsson; Perry M. Elliott; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Introduction: ARVC (Arrhythmogenic Right Ventricular Cardiomyopathy) is a heritable rare disease of the heart muscle, primarily affecting the right ventricle, that may cause arrhythmias and heart failure.Aim: The overall aim of this thesis was to study various aspects of genetic information and electrocardiography (ECG), for their use in diagnosis and risk evaluation in ARVC. LÄS MER