Sökning: "apoptotic regulators"

Visar resultat 16 - 20 av 31 avhandlingar innehållade orden apoptotic regulators.

  1. 16. New aspects on retinoic acid induced HL-60 granulocytic differentiation

    Författare :Agnè Kulytè; Tor Olofsson; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : The underlying mechanisms of myeloid cell differentiation are still not entirely elucidated. It is therefore an urgent task to extent the basis for a comprehensive model of granulocytes differentiation. A primary goal for studies has been the identification of differentiation markers. LÄS MER

  3. 17. Neuroinflammation in Alzheimer's disease : Focus on NF-κB and C/EBP transcription factors

    Författare :Veronica Ramberg; Kerstin Iverfeldt; Josep Saura; Stockholms universitet; []
    Nyckelord :Alzheimer’s disease; neuroinflammation; NF-κB; C EBP; apoptosis; caspases; FRET; Neurochemistry and Neurotoxicology; neurokemi och neurotoxikologi;

    Sammanfattning : Alzheimer's disease (AD) is the most common form of dementia among elderly. The disease is characterized by amyloid-β (Aβ) plaques, neurofibrillary tangles, loss of synapses and neurons and chronic neuroinflammation. LÄS MER

  4. 18. Maternal and neonatal anthropometry and growth factor expression and apoptosis in human placenta : a comparison between two populations

    Författare :Shahzad Akram; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The insulin-like growth factors (IGFs), IGF-binding proteins (IGFBPs), and IGFBP proteases, are key endocrine regulators of somatic growth and cellular proliferation. IGFs are involved in growth both pre- and postnatally. LÄS MER

  5. 19. Initiation of alternative pathway of complement, and development of novel liposomal coatings

    Författare :Anna Adler; Yuji Teramura; Penti Tengvall; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; immunology; complement system; C3; liposomes; polymer-lipids; Immunologi; Immunology;

    Sammanfattning : The complement system is a central part of the innate immune system, and is an essential part in recognizing and clearing non/altered-self surfaces in the body. This thesis comprises of projects in which the initiation of the alternative pathway (AP) of complement in the fluid phase as well on various artificial and lipid surfaces has been studied. LÄS MER

  7. 20. G1-phase cyclin expression in neoplastic B cells

    Författare :Richard Scuderi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Cell cycle; G1 phase; cyclin D; cyclin E; EBV; Burkitt s; B-ALL; B-CLL; apoptosis;

    Sammanfattning : By virtue of the role of G1-phase cyclin proteins as regulators of differentiation, proliferation, and apoptosis, their improper expression can lead to altered cellular homeostasis and tumor formation. Cyclins provide the regulatory partner for cyclin-cdk complexes whose enzymatic activity drives cell cycle progression. LÄS MER