Sökning: "NF-κB"
Visar resultat 1 - 5 av 101 avhandlingar innehållade ordet NF-κB.
1. Regulation of NF-κB by Calmodulin
Sammanfattning : Cells experience numerous external signals which they must respond to. Such signals arriving at the cell surface are transduced via various signal transduction pathways and often ultimately result in regulation of transcription. LÄS MER
2. Neuroinflammation in Alzheimer's disease : Focus on NF-κB and C/EBP transcription factors
Sammanfattning : Alzheimer's disease (AD) is the most common form of dementia among elderly. The disease is characterized by amyloid-β (Aβ) plaques, neurofibrillary tangles, loss of synapses and neurons and chronic neuroinflammation. LÄS MER
3. MEKK-1 and NF-κB Signaling in Pancreatic Islet Cell Death
Sammanfattning : Type 1 diabetes is an autoimmune disease resulting in the selective destruction of the insulin producing β-cells in the pancreas. Pro-inflammatory cytokines and the free radical nitric oxide (NO) have been implicated in mediating the destruction of β-cells, possibly through activation of the mitogen activated protein kinases (MAPKs) JNK, ERK and p38. LÄS MER
4. Regulation of activation of NF-κB by Calmodulin in T-lymphocytes
Sammanfattning : Nuclear factor kappa B (NF-kB) is a widely expressed family of transcription factors that are involved in a diverse number of processes. These include inflammation or differentiation, survival or apoptosis, and proliferation or cell cycle arrest. LÄS MER
5. Characterization and environmental influences on inflammatory and physiological responses
Sammanfattning : Pharmaceuticals are regularly released into the environment, in particular nonsteroidalanti-inflammatory drugs (NSAIDs) and antibiotics. The measuredconcentrations are relatively low and have therefore been considered to be harmless. LÄS MER
