Sökning: "C EBP"

Visar resultat 1 - 5 av 29 avhandlingar innehållade orden C EBP.

  1. 1. Neuroinflammation in Alzheimer's disease : Focus on NF-κB and C/EBP transcription factors

    Författare :Veronica Ramberg; Kerstin Iverfeldt; Josep Saura; Stockholms universitet; []
    Nyckelord :Alzheimer’s disease; neuroinflammation; NF-κB; C EBP; apoptosis; caspases; FRET; Neurochemistry and Neurotoxicology; neurokemi och neurotoxikologi;

    Sammanfattning : Alzheimer's disease (AD) is the most common form of dementia among elderly. The disease is characterized by amyloid-β (Aβ) plaques, neurofibrillary tangles, loss of synapses and neurons and chronic neuroinflammation. LÄS MER

  3. 2. Alzheimer Aβ peptides induce dysregulation of C/EBP and NF-кB in glial cells

    Författare :Malin Samuelsson; Kerstin Iverfeldt; Piet Eikelenboom; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer s disease; amyloid-β; astrocytes; C EBP; glia; microglia; neuroinflammation; NF-кB; Neurochemistry; Neurokemi; Neurochemistry and Neurotoxicology; neurokemi och neurotoxikologi;

    Sammanfattning : Inflammation is believed to contribute to neurodegeneration in Alzheimer’s disease (AD). AD in turn is believed to be a consequence of accumulated amyloid-β (Aβ) peptides, that subsequently form senile plaques, due to imbalance between production and clearance of Aβ. LÄS MER

  4. 3. C/EBP transcription factors in lung cellular differentiation and development

    Författare :Tove Berg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :C EBP transcription factors; lung; development; differentiation; glucocorticoid regulation;

    Sammanfattning : During embryonic development the lung is lined with a primitive epithelium. As development proceeds, the epithelium matures and differentiates into several cell types that together with cells of mesenchymal origin constitute the adult lung. LÄS MER

  5. 4. Studies of the C/EBP family of transcription factors : cloning, regulation, and expression

    Författare :Per Antonson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Basic leucine zipper; CCAATEnhancer Binding Protein; CEBP; DNA binding protein; Gene expression; Transcription factor;

    Sammanfattning : The CCAAT/Enhancer Binding Protein (C/EBP) family belongs to the basic leucine zipper class of transcription factors with a total of 6 members having been identified in this family so far. This gene family has been mainly implicated in regulation of cell specific gene expression and differentiation. LÄS MER

  7. 5. Transcriptional regulation of differentiation markers in the distal lung epithelium : a role for C/EBP factors

    Författare :Tobias Cassel; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Lung; C EBP; Cellular Differentiation; Clara Cell Secretory Protein; Development; Gene Expression; Transcriptional Regulation; CYP21B1; Promoter; Synergism; Nkx2.1;

    Sammanfattning : Late lung development is characterised by extensive cellular differentiation, resulting in a variety of specialised epithelial cell types. Although much is known of the extracellular signalling involved in lung morphogenesis, less is currently known of the intracellular developmental mechanisms that govern cellular differentiation. LÄS MER