Sökning: "aggregation mechanism N-terminus"
Hittade 4 avhandlingar innehållade orden aggregation mechanism N-terminus.
1. Unravelling protein stability and aggregation
Sammanfattning : Proteins are complex macromolecules that are fundamental to all living species. The stability of proteins are governed by non-covalent forces within the protein and between the protein and its surrounding environment. LÄS MER
2. On the molecular mechanisms of the amyloid β-peptide aggregation
Sammanfattning : The pathogenesis of Alzheimer’s disease is widely believed to be due to production and deposition of the amyloid β-peptide. Several variants of the Aβ peptide are known to exist in in vivo. Variations include mutations or additional functional groups attached to residue side chains and may affect the aggregation process. LÄS MER
3. Amyloid Beta – Biotherapy Target and Biotechnological Tool
Sammanfattning : Alzheimer’s disease is a progressive neurodegenerative disease characterized primarily by memory impairment and cognitive decline. As of 2020, an estimated 50 million people suffer from Alzheimer’s disease or related dementia and no disease-modifying treatment options are yet approved for clinical practice. LÄS MER
4. Fibrinogen-binding proteins from Staphylococcus aureus
Sammanfattning : Staphylococcus aureus produces a large number of proteins that specifically bind to molecules from plasma or from the human extracellular matrix where they are involved in processes associated with the colonization of the host tissues. At least six different fibrinogen-binding proteins have been identified from S. LÄS MER