Sökning: "protease substrate specificity"
Visar resultat 1 - 5 av 23 avhandlingar innehållade orden protease substrate specificity.
1. Haematopoietic Serine Proteases : A Cleavage Specificity Analysis
Sammanfattning : Mast cells are innate immune cells, historically involved in allergy responses involving IgE. Through this, they have earned a reputation as a fairly detrimental cell type. Their beneficial roles remain somewhat enigmatic although they clearly have the ability to modulate the immune system. LÄS MER
2. A thermostable alkaline protease from a new alkaliphilic Nesterenkonia sp
Sammanfattning : This thesis concerns a novel alkaline protease produced by an extremophilic microbial specie, designated as AL20, isolated from a feather sample collected at the shore of the alkaline soda lake Abjata in the Ethiopian Rift Valley. The isolate is a heterotrophic, alkaliphilic, halotolerant gram-positive, strictly aerobic, non-motile, non-spore forming bacterium. LÄS MER
3. Cutting Edge – Cleavage Specificity and Biochemical Characterization of Mast Cell Serine Proteases
Sammanfattning : It is well established that mast cells (MC) are key players in airway pathologies such as allergic asthma, but they are also known to contribute to host defense and tissue remodeling. MC serine proteases are the major protein components of mast cell granules and accordingly, are most likely involved in many aspects of MC function. LÄS MER
4. Cleavage Specificity of Mast Cell Chymases
Sammanfattning : Mast cells (MC) are potent inflammatory cells that are known primarily for their prominent role in IgE mediated allergies. However, they also provide beneficial functions to the host, e.g. in bacterial and parasitic defence. LÄS MER
5. The cell biology and catalytic properties of the nutrient-induced signaling endoprotease Ssy5
Sammanfattning : Cells continuously sense and respond to changes in the presence, quality and quantity of external and internal nutrients. Specific signaling proteases have been identified based on their roles in processing or destruction of distinct sets of downstream effector proteins in response to environmental cues. LÄS MER