Sökning: "coaggregation"
Hittade 5 avhandlingar innehållade ordet coaggregation.
1. Unravelling protein stability and aggregation
Sammanfattning : Proteins are complex macromolecules that are fundamental to all living species. The stability of proteins are governed by non-covalent forces within the protein and between the protein and its surrounding environment. LÄS MER
2. Fluorescent Probes and Protein Misfolding: Methods and Applications
Sammanfattning : Protein misfolding is a frequently occurring event in living cells and without the quality control, the consequences are disasterous. In this thesis, we studied protein misfolding in vitro by employing a variety of fluorophores, to either detect the highly ordered aggregates of intrinsically disordered proteins/peptides or slight misfolding of a natively folded protein. LÄS MER
3. If I only had a brain : epidemiological studies of Parkinson's disease
Sammanfattning : Parkinson’s disease (PD) is an aging-related movement disorder caused by selective degeneration of dopaminergic neurons in the substantia nigra in the midbrain. Onset of PD symptoms, which include tremor, bradykinesia and rigidity (together referred to as parkinsonism), is most common after age 65. LÄS MER
4. Adenosine receptor/dopamine receptor interactions : molecular and biochemical aspects
Sammanfattning : The dopamine receptors have been shown to be involved in a variety of higher brain functions, such as motor control, cognition and affective states. Agonist and antagonists of dopamine receptors are widely used to treat disorders such as Parkinson's disease and schizophrenia, respectively. LÄS MER
5. Convergent etiology among schizophrenia, eating disorders, and other medical conditions
Sammanfattning : Schizophrenia and eating disorders (EDs) are complex traits with considerable somatic and psychiatric morbidity. Despite distinct diagnostic criteria and few symptoms in common, significant genetic correlations between schizophrenia and anorexia nervosa (AN) have been illustrated in several recent genomic studies. LÄS MER