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Visar resultat 16 - 20 av 229 avhandlingar som matchar ovanstående sökkriterier.

  1. 16. Doppler evaluation of coronary blood flow and coronary flow reserve - Clinical and experimental studies

    Författare :Gylfi Oskarsson; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pediatrics; Pediatri; Cardiovascular system; Kardiovaskulära systemet; fetal asphyxia; transposition of the great arteries; dilated cardiomyopathy; aortic stenosis; child; neonate; adenosine; coronary flow reserve; Doppler; coronary flow;

    Sammanfattning : Heart diseases in children cause different combinations of myocardial hypertrophy, increased intra-ventricular pressures, volume overload and decreased oxygen saturation. This may affect basal coronary flow and the ability of the heart to maximally increase coronary flow. LÄS MER

  3. 17. Mechanisms of Ischemic Brain Injury- studies in murine hippocampal slice cultures

    Författare :Anna Rytter; Sektion IV; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neurophysiology; Neurologi; neuropsykologi; neuropsychology; Neurology; adenosine; caspases; hypothermia; in vitro; hippocampus; ischemia; neurofysiologi;

    Sammanfattning : Cerebral ischemia is a major cause of mortality and morbidity in the western world. Even though much effort has been put into research and development of effective drugs against ischemic damage there is to date no effective pharmacological brain protective treatment. LÄS MER

  4. 18. Ischemic Cell Death in the CNS - applications of a new in vitro model

    Författare :Tobias Cronberg; Sektion IV; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuropsykologi; Neurologi; Neurology; astrocyte; stroke; adenosine; hyperglycaemia; glucose; free radicals; calcium; in vitro; brain ischemia; slice; neuropsychology; neurofysiologi; neurophysiology;

    Sammanfattning : Ischemic brain damage is a common cause of death and disability. A global ischemic insult is usually the result of a transient cardiac arrest while occlusion of cerebral blood vessels leads to focal ischemic lesions, commonly termed stroke. LÄS MER

  5. 19. Modeling Biochemical Network Involved in Striatal Dopamine Signaling

    Författare :Anu G. Nair; Jeanette Hellgren Kotaleski; Omar Gutierrez Arenas; Upinder Singh Bhalla; Jakob Kisbye Dreyer; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dopamine signaling; Striatum; Reward learning; Acetylcholine; Mass-action modeling; FRET biosensor; Adenosine; Eligibility trace; Computer Science; Datalogi;

    Sammanfattning : In this thesis, I studied the molecular integration of reward-learning related neuromodulatory inputs by striatal medium-sized projection neurons (MSNs) using mass-action kinetic modeling.It is known that, in reward learning, an unexpected reward results in transient elevation in dopamine (peak) whereas omission of an expected reward leads to transient dopamine decrease (dip). LÄS MER

  7. 20. Studies on mitochondrial adenosine triphosphatase : uncoupler-reversible inhibition of mitochondrial ATPase and related enzymes by metal chelates of bathophenenthroline

    Författare :Christine Carlsson-Skwirut; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : The mitochondrial ATPase constitutes the terminal enzyme of oxidative phosphorylation and is, together with similar enzymes present in chloroplasts and bacteria, responsible for the synthesis of ATP from ADP and Pi during electron transport. The enzyme consists of an extrinsic, catalytically active part, called Fl, that is structurally and functionally linked to an intrinsic, proton-translocating device, called Fo. LÄS MER