Sökning: "Toll-like receptor"

Visar resultat 11 - 15 av 106 avhandlingar innehållade orden Toll-like receptor.

  1. 11. Microbial and maternal influences on allergic sensitization during childhood: defining a role for monocytes

    Författare :Shanie Saghafian Hedengren; Eva Sverremark-Ekström; Susan Prescott; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Monocytes; allergic sensitization; maternal allergy; Toll-like receptor; p38-MAPK; IL-6; Epstein-Barr virus; early-life microbial exposure; NK cells; IFN-γ; Immunology; Immunologi; immunologi; Immunology;

    Sammanfattning : Allergic diseases are influenced by genetics and the environment. Maternal allergy appears to confer a higher risk for allergic sensitization than paternal allergy, suggesting an in utero influence. LÄS MER

  3. 12. Role of toll-like receptors in host responses to mucosal bacterial infections

    Författare :Fredrik Bäckhed; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The first contact between invading bacteria and the host occurs at the mucosal surface. Interestingly, the mucosal linings of different organs are exposed to bacteria to various degrees. LÄS MER

  4. 13. Recruitment, Differentiation, and Function of monocytes during Salmonella infection

    Författare :Anna Rydström; Göteborgs universitet; []
    Nyckelord :Salmonella; Monocyte; Neutrophil; Chemokine; Toll-like receptor; Differentiation;

    Sammanfattning : Monocytes are a heterogeneous population in the blood with an enormous plasticity whose fate and functions are dictated by the microenvironment. They are phenotypically and functionally related to neutrophils and dendritic cells (DCs) and share an overlapping expression pattern of surface molecules with these cells. LÄS MER

  5. 14. Role of Neutrophils and Innate Immune Mechanisms in Urinary Tract Infections

    Författare :Björn Frendéus; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mikrobiologi; mycology; virology; bacteriology; Microbiology; Mucosal immunology; Infection Resistance; Neutrophils; Toll-like receptors; Urinary Tract Infections; Chemokine receptors; bakteriologi; virologi; mykologi;

    Sammanfattning : Urinary tract infections (UTI) are among the most common infections in man. Despite their prevalence, information on the molecular mechanisms defects that explain the increased susceptibility to disease are lacking. LÄS MER

  7. 15. Dendritic cell maturation and death during Salmonella infection. Role of pro-inflammatory cytokines and MyD88

    Författare :Malin Sundquist; Göteborgs universitet; []
    Nyckelord :Dendritic cells; Costimulatory molecules; Bacterial infection; Pro-inflammatory cytokines; Toll-like receptors; Ag presentation; Cell death;

    Sammanfattning : The costimulatory molecules CD80 and CD86 are required for the ability of dendritic cells (DC) to induce both tolerance and immunity. This thesis investigates the control of CD80/CD86 upregulation in vivo on DC during Salmonella infection. LÄS MER