Sökning: "Synaptic Transmission"

Visar resultat 11 - 15 av 75 avhandlingar innehållade orden Synaptic Transmission.

  1. 11. Mechanisms underlying sustained synaptic release of glutamate

    Författare :Oleg Shupliakov; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :synaptic transmission; synaptic vesicle proteins; synapsin; glutamate; glutamine; glutamate uptake; glia; spinal cord; hippocampus; neuromuscular junction; lamprey; crayfish; mouse.;

    Sammanfattning : Fast communication between neurons in the brain is mediated mainly by amino acid transmitters, such as glutamate, GABA and glycine. These transmitters are stored in small synaptic vesicles which undergo exocytosis at synaptic release sites (active zones) in response to action potentials. LÄS MER

  3. 12. Astrocyte-mediated short-term synaptic depression

    Författare :My Andersson; Göteborgs universitet; []
    Nyckelord :glutamate; glia; plasticity; synapse; hippocampus;

    Sammanfattning : Short-term synaptic plasticity, the activity-dependent regulation of synaptic efficacy that occurs in the timeframe of milliseconds to seconds, is a fundamental property of the synapse, mostly attributed to changes in release probability. These changes are commonly ascribed to intrinsic mechanisms in the presynaptic terminal and to different transmitters acting on the presynaptic terminal. LÄS MER

  4. 13. Synaptic vesicle endocytosis studied in a living synapse

    Författare :Helge Gad; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :synapse; synaptic vesicles; endocytosis; clathrin; calcium; dynamin; endophilin; amphiphysin; synaptojanin; microinjection; electron microscopy;

    Sammanfattning : Neurons in the central nervous system communicate by transmitting electrical signals at special sites of contact called synapses. Synapses contain neurotransmitter-filled synaptic vesicles, which fuse with the presynaptic plasma membrane. The neurotransmitter diffuses to the neighboring neuron and triggers a new electrical signal. LÄS MER

  5. 14. The claustrum is a highway not a hub : organizing principles of claustrocortical synaptic transmission

    Författare :Zhi Chia; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The claustrum (CLA) is a brain nucleus wedged between the cortex and striatum. The behaviors it has been implicated in include consciousness, attention, memory and salience detection; dysfunction of CLA circuits is associated with schizophrenia, epilepsy, parkinsonism and disrupted consciousness. LÄS MER

  7. 15. Ethanol-induced modulation of dopamine transmission and synaptic activity in striatal subregions - focus on inhibitory receptors

    Författare :Rhona B. C. Clarke; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; dopamine; ethanol; acetaldehyde; striatum; glycine receptor; GABA A receptor;

    Sammanfattning : Background: Alcoholism is a chronic brain disease, affecting neurocircuitries involved in reward and learning. The rewarding effects of alcohol (ethanol) are believed to result from increased dopamine levels in the nucleus accumbens (nAc) via the mesolimbic system. LÄS MER