Sökning: "synapsin"
Visar resultat 1 - 5 av 7 avhandlingar innehållade ordet synapsin.
1. Coordination of endocytosis at the synaptic periactive zone
Sammanfattning : Neurons in the central nervous system communicate via specialized junctions called synapses. Neurotransmitter-filled vesicles are clustered at these junctions, where they are released in response to synaptic activity. To sustain reliable neurotransmission the synaptic vesicles are recycled locally. LÄS MER
2. Mechanisms underlying sustained synaptic release of glutamate
Sammanfattning : Fast communication between neurons in the brain is mediated mainly by amino acid transmitters, such as glutamate, GABA and glycine. These transmitters are stored in small synaptic vesicles which undergo exocytosis at synaptic release sites (active zones) in response to action potentials. LÄS MER
3. Intraocular and intracranial transplantation of neural tissue : Studies on hypothalamic and hippocampal neuros
Sammanfattning : Previous studies has demonstrated the possibility to transplant monoaminergic neurons intracranially and to the anterior chamber of the eye, where these neurons continue to develop into functional, transmitter expressing cells. In the present study, investigations were undertaken to examine the development of transplanted hypothalamic and hippocampal neurons in the rat. LÄS MER
4. Development of proteomic methods for studying cerebrospinal fluid proteins involved in Alzheimer´s disease
Sammanfattning : Alzheimer's disease (AD) is the most common cause of dementia in western countries. The main neuropathological findings in the AD brain are senile plaques, neurofibrillary tangles and degeneration of neurons and synapses. LÄS MER
5. The N-methyl-D-aspartate receptor subunit NR3A : cloning, expression and interacting proteins
Sammanfattning : This thesis focuses on the subunit NR3A, which together with subunits NR1, NR2A-NR2D and NR3B builds the excitatory glutamate receptor N-methyl-D-aspartate (NMDA). The receptor is most likely a tetramer, containing at least one NR1, probably two NR2 and sometimes one NR3 subunit. LÄS MER