Sökning: "amphiphysin"

Visar resultat 1 - 5 av 6 avhandlingar innehållade ordet amphiphysin.

  1. 1. Coordination of endocytosis at the synaptic periactive zone

    Författare :Emma Evergren; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Synapse; endocytosis; clathrin; dynamin; amphiphysin; synapsin; intersectin; actin cytoskeleton; immunogold electron microscopy.;

    Sammanfattning : Neurons in the central nervous system communicate via specialized junctions called synapses. Neurotransmitter-filled vesicles are clustered at these junctions, where they are released in response to synaptic activity. To sustain reliable neurotransmission the synaptic vesicles are recycled locally. LÄS MER

  2. 2. Synaptic vesicle endocytosis studied in a living synapse

    Författare :Helge Gad; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :synapse; synaptic vesicles; endocytosis; clathrin; calcium; dynamin; endophilin; amphiphysin; synaptojanin; microinjection; electron microscopy;

    Sammanfattning : Neurons in the central nervous system communicate by transmitting electrical signals at special sites of contact called synapses. Synapses contain neurotransmitter-filled synaptic vesicles, which fuse with the presynaptic plasma membrane. The neurotransmitter diffuses to the neighboring neuron and triggers a new electrical signal. LÄS MER

  3. 3. RICH-1, a Multifunctional RhoGAP Domain-containing Protein, Involved in Regulation of the Actin Filament System and Membrane-trafficking

    Författare :Ninna Richnau; Pontus Aspenström; Carl-Henrik Heldin; Bengt Hallberg; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; Rho GTPase; RhoGAP; actin; BAR domain; membrane-trafficking; formin homology proteins; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi;

    Sammanfattning : The Rho GTPases, which are related to the Ras family of proto-oncogenes, have been found to have important roles in regulating the morphogenic and migratory properties of eukaryotic cells. In addition, these proteins have been shown to regulate aspects of cell signaling, cell growth, cell division and cell survival. LÄS MER

  4. 4. Dementia Proteomics

    Författare :Julia Remnestål; Peter Nilsson; Anna Månberg; Pieter Jelle Visser; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dementia; Proteomics; Alzheimer s disease; Frontotemporal dementia; Antibody array; Suspension bead array; Cerebrospinal fluid; Protein profiling; Biomarker discovery; Bioteknologi; Biotechnology;

    Sammanfattning : The term dementia encompass a number of conditions arising as a consequence of tissue degeneration in the brain. This degeneration is caused by molecular events occurring on a cellular level including inflammation, defective waste disposal and accumulation of insoluble proteins and peptides. LÄS MER

  5. 5. Structure studies of membrane associated proteins by transmission electron microscopy

    Författare :Zuoneng Wang; Carsten Mim; Anna Sundborger Lunna; KTH; []
    Nyckelord :peripheral membrane protein PMP ; BAR protein; membrane curvature; actin dynamic; transmission electron microscopy; liposomes; Technology and Health; Teknik och hälsa;

    Sammanfattning : Cell membranes need to change their shapes during many cellular processeslike protein trafficking, cytokinesis and membrane homeostasis. The lattershuttles lipids, synthesized in the endoplasmic reticulum, to all membranouscompartments. LÄS MER