Sökning: "Structure-Function"

Visar resultat 11 - 15 av 182 avhandlingar innehållade ordet Structure-Function.

  1. 11. Structure-function relationships of hormone-sensitive lipase

    Författare :Torben Österlund; Institutionen för translationell medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Proteins; mutagenesis; domain; fold; catalytic triad; lipase; structure; enzymology; Proteiner; enzymologi;

    Sammanfattning : The primary role of hormone-sensitive lipase (HSL), an 84 kDa enzyme of 768 amino acids (in the rat protein), is to hydrolyse stored triacylglycerols in adipocytes of white adipose tissue. Catecholamines and insulin regulate lipolysis through cellular signalling. LÄS MER

  3. 12. Evolutionary and structure-function studies of neurotrophins

    Författare :Klas Kullander; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  4. 13. The transaldolase family : structure, function and evolution

    Författare :Stina Thorell; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The transaldolase gene family includes representatives from all kingdoms of life and the encoded enzymes are important for carbohydrate metabolism. The family can be divided into two subfamilies; Classical transaldolases and the MipB/TalC proteins. LÄS MER

  5. 14. Tunnels and Grooves : Structure-Function Studies in Two Disparate Enzymes

    Författare :Daniel Ericsson; Sherry Mowbray; Guy Dodson; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mycobacterium tuberculosis; ribonucleotide reductase; peptide inhibitors; fluorescence polarization; lipase; interfacial activation; hydrolase; X-ray structure; substrate specificity; Structural biology; Strukturbiologi;

    Sammanfattning : This thesis describes structural and binding studies in enzymes from two different  organisms: ribonucleotide reductase from Mycobacterium tuberculosis (RNR) and lipase A from Candida antarctica (CalA).RNR is viable as a target for new drugs against the causative agent of tuberculosis. LÄS MER

  7. 15. Improved solid phase synthesis of apamin, the principal neurotoxin of bee venom : structure-function studies based on synthetic analogues

    Författare :Bengt E. B. Sandberg; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP;

    Sammanfattning : .... LÄS MER