Sökning: "interfacial activation"

Visar resultat 1 - 5 av 20 avhandlingar innehållade orden interfacial activation.

  1. 1. Tunnels and Grooves : Structure-Function Studies in Two Disparate Enzymes

    Författare :Daniel Ericsson; Sherry Mowbray; Guy Dodson; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mycobacterium tuberculosis; ribonucleotide reductase; peptide inhibitors; fluorescence polarization; lipase; interfacial activation; hydrolase; X-ray structure; substrate specificity; Structural biology; Strukturbiologi;

    Sammanfattning : This thesis describes structural and binding studies in enzymes from two different  organisms: ribonucleotide reductase from Mycobacterium tuberculosis (RNR) and lipase A from Candida antarctica (CalA).RNR is viable as a target for new drugs against the causative agent of tuberculosis. LÄS MER

  3. 2. On the Diluent and Solvent Effects in Liquid-Liquid Extraction Systems based on Bis-triazine-bipyridine (BTBP) ligands

    Författare :Elin Löfström Engdahl; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Solvent effects; Diluent effects; GANEX; Interfacial tension; Density;

    Sammanfattning : Used nuclear fuel is dangerous for mankind and her environment for a long time. If however, the minor actinides together with uranium and plutonium could be transmuted, i.e. transformed, into more shortlived or stable isotopes the volume of the waste could be significantly reduced together with a reduction in the radiotoxicity. LÄS MER

  4. 3. Surface potential dynamics on insulating polymers for HVDC applications

    Författare :Shahid Alam; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; dielectric spectroscopy; silicone rubber; intrinsic conduction; surface potential decay; activation energy; electric conductivity; HVDC insulation;

    Sammanfattning : The use of high voltage direct current (HVDC) technology in power transmission systems is continuously expanding. Nowadays, HVDC transmissions operate at voltages up to 800 kV and higher levels are being developed. LÄS MER

  5. 4. Molecular Structure, Interfacial Chain Topology, Electronic Structure and Fracture Toughness of Polyethylene: A Multiscale Computational Study

    Författare :Ali Moyassari Sardehaei; Ulf W. Gedde; Gregory C. Rutledge; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : The structure of semicrystalline polyethylene (PE) strongly affects its properties. Two important structural features, namely the concentrations of tie chains and entanglements cannot be directly assessed using experimental techniques. LÄS MER

  7. 5. Theoretical Studies of G-Protein-Coupled Receptors

    Författare :Xianqiang Sun; Yaoquan Tu; Lennart Nilsson; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biological Physics; Biologisk fysik;

    Sammanfattning : The family of G-protein-coupled receptors (GPCRs) contains the largest number of drug targets in the human body, with more than a quarter of the clinically used drugs targeting them. Because of the important roles GPCRs play in the human body, the mechanisms of activation of GPCRs or ligands binding to GPCRs have captivated much research interest since the discovery of GPCRs. LÄS MER