Sökning: "Structure-Function"

Visar resultat 21 - 25 av 181 avhandlingar innehållade ordet Structure-Function.

  1. 21. Structure-function studies of plasminogen activator inhibitor-1

    Författare :Guang-Chao Sui; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :PAI-1; site-directed mutagenesis; structure and function; stability;

    Sammanfattning : Plasminogen activator inhibitor-I (PAI-1) is an important physiological inhibitor of tissue-type plasminogen activator (tPA) and urine-type plasminogen activator (uPA). High plasma levels of PAI-1 correlate to thrombotic disease, and low levels can be connected to a bleeding tendency. LÄS MER

  3. 22. Structure, function and metabolic stability of antisense RNAs

    Författare :Fredrik Söderbom; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Microbiology; Mikrobiologi; Microbiology; Mikrobiologi; mikrobiologi; Microbiology;

    Sammanfattning : Antisense RNAs usually are small, highly structured, unstable RNAs that control a varietyof different biological processes. They exert their effect by binding to complementarytarget RNAs and thereby inhibit their functions. LÄS MER

  4. 23. Phrygian rock-cut shrines and other religious monuments : a study of structure, function and cult practice

    Författare :Susanne Berndt-Ersöz; Stockholms universitet; []
    Nyckelord :HUMANIORA; HUMANITIES; Kultplatser; Frygien;

    Sammanfattning : .... LÄS MER

  5. 24. Aldolases for Enzymatic Carboligation : Directed Evolution and Enzyme Structure-Function Relationship Studies

    Författare :Huan Ma; Mikael Widersten; Wolf-Dieter Fessner; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; aldolase; 2-deoxyribose-5-phosphate aldolase; fructose-6-phosphate aldolase; directed evolution; enzyme dynamics; Biokemi; Biochemistry;

    Sammanfattning : The research summarized in this thesis focuses on directed evolution and enzyme mechanism studies of two aldolases: 2-deoxyribose-5-phosphate aldolase (DERA) and fructose-6-phosphate aldolase (FSA).Aldolases are nature’s own catalysts for one of the most fundamental reactions in organic chemistry: the formation of new carbon-carbon bonds. LÄS MER

  7. 25. The Structure-Function Relationship and Evolution of Deoxyribonucleoside Kinases

    Författare :Zeeshan Mutahir; Molekylär cellbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : The synthesis of deoxyribonucleoside triphosphates (dNTPs), building blocks of DNA, can be achieved by two different pathways in the cell. One is called de novo synthesis and the other is known as salvage pathway. The de novo pathway involves synthesis of dNTPs by utilizing basic molecules like sugars, amino acids, CO2, NH3, etc. LÄS MER