Sökning: "Somatic Disease"

Visar resultat 1 - 5 av 166 avhandlingar innehållade orden Somatic Disease.

1. 1. Psychological processes in somatic disease

   Författare :Noomi Elander Lindberg; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The course of disease was investigated in three studies of patients with rheumatoid arthritis (RA). The aim was to explore changes in clinical course during and after psychodynamically oriented psychotherapy, with one session of 60-90 minutes per week for 3.3 years as a median. LÄS MER

3. 2. Complex disease genetics : Utilising targeted sequencing and homogeneous ancestry

   Författare :Argyri Mathioudaki; Kerstin Lindblad-Toh; Panagiotis Deloukas; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; ankylosing spondylitis; breast cancer; targeted sequencing; Sweden; genetics; population stratification.; Molekylär genetik; Molecular Genetics;

   Sammanfattning : The complex disease investigations presented in this thesis aimed to provide new information regarding underlying genetics by using targeted sequencing and ethnically homogeneous cohorts. This work moved past current methodologies and addressed data stratification issues, that might have been hindering new findings. LÄS MER

4. 3. Somatic Mutations in Breast Cancer Genomes : Discovery and Validation of Breast Cancer Genes

   Författare :Xiang Jiao; Tobias Sjöblom; Anne-Lise Børresen-Dale; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; breast cancer; cancer gene; pathway; somatic mutation; structural alteration; sequencing; whole genome amplification; Genetics; Genetik; Medical Genetics; Medicinsk genetik;

   Sammanfattning : Breast cancer is the most common cancer in women worldwide. However, the genetic alterations that lead to breast cancer are not fully understood. This thesis aims to identify novel genes of potential mechanistic, diagnostic or therapeutic interest in breast cancers by mutational analysis and whole-genome sequencing. LÄS MER

5. 4. Food in older men with somatic diseases : Eating habits and approaches to food-related activities

   Författare :Kerstin Kullberg; Anna Cristina Åberg; Birgitta Sidenvall; Anita Björklund; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; actvities of daily living; arthritis rheumatoid; cookery; meal patterns; men; nutrition; older people; Parkinson disease; stroke; Caring sciences; Vårdvetenskap;

   Sammanfattning : The overall aim was to improve the knowledge and understanding of eating habits of older men with somatic diseases, and the men's perceptions about managing food-related habits, such as grocery shopping and cooking. A total of 67 men between 64 and 89 years of age were visited in their homes on two occasions with 1-2 weeks in between. LÄS MER

7. 5. Somatic and occupational outcomes in adult ADHD : epidemiology studies based on real-world data

   Författare :Lin Li; Henrik Larsson; Zheng Chang; Qi Chen; Mark Taylor; Argyris Stringaris; Örebro universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ADHD; Comorbidities; Obesity; Dietary habits; ADHD medication; Cardiovascular disease; Epidemiology; Casual inference; Adults;

   Sammanfattning : Attention-deficit/hyperactivity disorder (ADHD) is one of the most common neurodevelopmental disorders, characterized by inattention or hyperactivity–impulsivity, or both. ADHD is a multifactorial disorder influenced by the complex interplay between genetic and environmental risk factors, but a detailed understanding of the causal status of these factors is lacking. LÄS MER