Sökning: "Pharmaceutical industry"

Visar resultat 11 - 15 av 103 avhandlingar innehållade orden Pharmaceutical industry.

  1. 11. Optimal (Adaptive) Design and Estimation Performance in Pharmacometric Modelling

    Författare :Alan Maloney; Ulrika Simonsson; Mats Karlsson; Andy Grieve; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Phase II; dose response; optimal design; adaptive design; exposure response; count data;

    Sammanfattning : The pharmaceutical industry now recognises the importance of the newly defined discipline of pharmacometrics. Pharmacometrics uses mathematical models to describe and then predict the performance of new drugs in clinical development. LÄS MER

  3. 12. ChemGPS-NP and the Exploration of Biologically Relevant Chemical Space

    Författare :Josefin Rosén; Anders Backlund; Johan Gottfries; Robert Verpoorte; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacognosy; Farmakognosi; Pharmacognosy; farmakognosi;

    Sammanfattning : Chemical space is basically infinite, and comprises all molecules that could possibly exist. Intelligent ways to efficiently navigate through chemical space and to select promising compounds in drug discovery are important tasks, and the focus of this thesis. In this work a new model for chemical space navigation, ChemGPS-NP, was developed. LÄS MER

  4. 13. Heterogeneities in polymer gels: Effects on swelling and mechanical properties

    Författare :Mikael Larsson; Chalmers tekniska högskola; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gel; Phase separation; Heterogeneities; Polyacrylic acid.; HPMC; Glass transition temperature; Microfibrillated cellulose; Filler; Elastomer;

    Sammanfattning : Polymeric hydrogels is a class of scientifically interesting materials that are being extensively studied. They are found in numerous applications within; drug delivery, hygiene products, food industry, analytical chemistry, etc. In addition, polymeric hydrogels have promising future applications as; cell scaffolds, implants, sensors, etc. LÄS MER

  5. 14. Leadership development in R&D intensive organizations : an explorative approach to understanding characteristics of needs and opportunities for leadership development within a pharmaceutical organization

    Författare :Kina Mulec; Chalmers tekniska högskola; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; professional worker; dual role; R D organization; collaborative research; leadership; pharmaceutical industry; leadership development;

    Sammanfattning : .... LÄS MER

  7. 15. Fundamental and Regulatory Aspects of UHPLC in Pharmaceutical Analysis

    Författare :Dennis Åsberg; Torgny Fornstedt; Jörgen Samuelsson; Gert Desmet; Karlstads universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Liquid chromatography; UHPLC; Pharmaceutical analysis; Adsorption isotherm; Design of experiments; Quality control; Kemi; Chemistry;

    Sammanfattning : Ultra-high performance liquid chromatography (UHPLC) provides a considerable increase in throughput compared to HPLC and a reduced solvent consumption. The implementation of UHPLC in pharmaceutical analysis, e.g. LÄS MER