Sökning: "Peripheral arthritis"

Visar resultat 11 - 15 av 93 avhandlingar innehållade orden Peripheral arthritis.

1. 11. Associations Between Rheumatoid Arthritis and Malignant Lymphomas

   Författare :Eva Baecklund; Christer Sundström; Anders Ekbom; Roger Hällgren; Tore Kvien; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; rheumatoid arthritis; malignant lymphoma; diffuse large B-cell lymphoma; disease activity; disease modifying anti-rheumatic drug; Epstein-Barr virus; germinal centre-like non-germinal centre-like subtype; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin;

   Sammanfattning : Patients with rheumatoid arthritis (RA) are at increased risk of developing malignant lymphoma, although details about this association remain unclear. The aims of this thesis were to investigate risk factors for lymphoma in patients with RA and to characterize these lymphomas regarding subtype, presence of Epstein-Barr virus (EBV), clinical manifestations and prognosis. LÄS MER

3. 12. A Clinical and Genetic Study of Psoriatic Arthritis

   Författare :Gerd-Marie Alenius; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Public health; Psoriatic arthritis; prevalence; inflammatory manifestations; genetic loci; HLA; TNFB; Folkhälsomedicin; Public health medicine research areas; Folkhälsomedicinska forskningsområden; Clinical Genetics; klinisk genetik;

   Sammanfattning : Psoriatic arthritis (PsA) is an inflammatory joint disease associated with psoriasis. PsA has a heterogeneous pattern, expressed by different manifestations such as mild mono-oligoarthritis or very severe, erosive and destructive polyarthritis. Measurable inflammatory activity is not always prominent. LÄS MER

4. 13. Modulation of immune responses in murine collagen induced arthritis

   Författare :Fredrik Bäckström; Göteborgs universitet; []
   Nyckelord :Experimental arthritis; type II collagen; immunomodulation; oral tolerance;

   Sammanfattning : Murine collagen-induced arthritis (CIA) is the most common model for studying human rheumatoid arthritis (RA). Autologous or heterologous type II collagen (CII) emulsified in Freund´s complete adjuvant induces arthritis in susceptible mice, which is histopathologically similar to RA. LÄS MER

5. 14. Neuropeptides in temporomandibular joint arthritis

   Författare :Anna Appelgren; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Adjuvant; Arthritis; Calcitonin gene-related peptide; Glucocorticosteroids; Hippocampus; Hyperalgesia; Hypothalamus; Hypothalamo-pituitary-adrenal axis; Intra-articular temperature; Neurokinin A; Neuropeptides; Neuropeptide Y; Nociception; Pain; Pituitary; Pressure pain threshold; Rheumatoid arthritis; Substance P; Synovial fluid; Temporomandibularjoint; Visual analog scale;

   Sammanfattning : Involvement of the peripheral and central nervous systems in the pathophysiology of arthritis has been suggested and neuropeptides are thought to participate in the mediation and modulation of the inflammatory process. The main objective of the clinical studies was to investigate the relationship between the presence of neuropeptides in the synovial fluid of the temporomandibular joint (TMJ) and the stomatognathic symptoms and signs, including the intra-articular temperature (IAT), in patients with TMJ arthritis. LÄS MER

7. 15. B cell subpopulations in the pathogenesis of rheumatoid arthritis

   Författare :Katrin Thorarinsdottir; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; B cells; Rheumatoid arthritis; Joint destruction; DAS28; CD21- low B cells;

   Sammanfattning : B cell depleting therapy has proven to be an effective treatment in rheumatoid arthritis (RA), a disease characterized by the presence of autoantibodies against citrullinated proteins (ACPA) and the Fc portion of IgG (rheumatoid factor, RF). This demonstrates the vital role B cells play in the disease. LÄS MER