Sökning: "Eva Baecklund"

Hittade 4 avhandlingar innehållade orden Eva Baecklund.

  1. 1. Associations Between Rheumatoid Arthritis and Malignant Lymphomas

    Författare :Eva Baecklund; Christer Sundström; Anders Ekbom; Roger Hällgren; Tore Kvien; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; rheumatoid arthritis; malignant lymphoma; diffuse large B-cell lymphoma; disease activity; disease modifying anti-rheumatic drug; Epstein-Barr virus; germinal centre-like non-germinal centre-like subtype; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin;

    Sammanfattning : Patients with rheumatoid arthritis (RA) are at increased risk of developing malignant lymphoma, although details about this association remain unclear. The aims of this thesis were to investigate risk factors for lymphoma in patients with RA and to characterize these lymphomas regarding subtype, presence of Epstein-Barr virus (EBV), clinical manifestations and prognosis. LÄS MER

  3. 2. Studies of drug safety in the treatment of rheumatoid arthritis

    Författare :Johanna Karlsson Sundbaum; Eva Baecklund; Mia Wadelius; Pär Hallberg; Peter Michaelson; Gerd-Marie Alenius; Uppsala universitet; []
    Nyckelord :Drug safety; Rheumatoid arthritis; Hepatotoxicity; Methotrexate; MTHFR; GWAS; tuberculosis; screening;

    Sammanfattning : Rheumatoid arthritis (RA) is a chronic inflammatory disease affecting mainly smaller joints. Patients are at risk for complications as joint destruction, but starting treatment soon after onset of disease, has reduced the risk for complications. LÄS MER

  4. 3. Posttransplant Lymphoproliferative Disorders : Studies of Epstein-Barr Virus, Regulatory T Cells and Tumor Origin

    Författare :Amelie Kinch; Karlis Pauksens; Gunilla Enblad; Eva Baecklund; Harald Holte; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PTLD; Lymphoma; Epstein-Barr Virus; EBV DNAemia; FoxP3; Treg; Microenvironment; Cell of Origin; Recipient; Transplantation; Immunosuppression; Hepatitis C; Survival; Medicinsk vetenskap; Medical Science;

    Sammanfattning : Epstein-Barr virus (EBV) infects almost all humans and establishes lifelong latency in B cells. Posttransplant lymphoproliferative disorder (PTLD) is a rare but serious complication after transplantation triggered by immunosuppression and often related to EBV infection. LÄS MER

  5. 4. Lymphoma studies in patients with Sjögren's syndrome

    Författare :Lilian Vasaitis; Eva Baecklund; Lars Rönnblom; Thomas Mandl; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Sjögren s syndrome; primary Sjögren s syndrome; lymphoma; IgG4-related disease; Medicinsk vetenskap; Medical Science;

    Sammanfattning : Patients with primary Sjögren’s syndrome (pSS) are at increased risk of developing malignant lymphoma. The studies in this thesis aim at broadening our understanding of the association between these two conditions. LÄS MER