Sökning: "Parathyroid gland"

Visar resultat 6 - 10 av 14 avhandlingar innehållade orden Parathyroid gland.

1. 6. Transcriptional regulation of genes expressed in the parathyroid gland

   Författare :Anders Knutson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Kirurgi; Surgery; Kirurgi; Surgery; kirurgi;

   Sammanfattning : A dynamic interplay between promoter sequences and transcription factors ensures that genes are expressed at appropriate levels in each cell throughout the body. In the present investigation, the promoters of two different genes encoding proteins involved in parathyroid cell function and calcium homeostasis were studied. LÄS MER

3. 7. Interaction between Calcium, Calciotropic Hormones and the Gastrin-ECL-cell Axis

   Författare :Rebecca Gagnemo Persson; Hälsofrämjande komplexa interventioner; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pharmacognosy; Pharmacological sciences; rat; chicken; parathyroid gland; stomach; vitamin D; PTH; CT; calciotropic hormones; Gastrin; calcium; ECL cell; pharmacy; toxicology; Farmakologi; farmakognosi; farmaci; toxikologi; Histology; cytochemistry; histochemistry; tissue culture; Histologi; cytokemi; histokemi; vävnadskultur;

   Sammanfattning : Calcium homeostasis involves mainly the interaction of PTH, vitamin D and CT. The stomach may be important for calcium homeostasis. Gastric acid is thought to mobilize calcium from the diet, thereby facilitating the absorption of calcium in the small intestines. LÄS MER

4. 8. Wnt/β-Catenin Signalling in Parathyroid Tumours

   Författare :Peyman Björklund; Gunnar Westin; Göran Åkerström; Tommy Andersson; Uppsala universitet; []
   Nyckelord :Surgery; Hyperparathyroidism; β-catenin; Mutation; Human parathyroid cell line; LRP5; Alternative splicing; Kirurgi;

   Sammanfattning : Primary hyperparathyroidism (pHPT) due to parathyroid tumours with hypersecretion of parathyroid hormone and hypercalcaemia is a common disease with incompletely understood etiology affecting more than 1 % of the population, primarily postmenopausal women. In secondary hyperparathyroidism (sHPT), parathyroid tumours develop in response to calcium and vitamin D deficiency generally in patients with uraemia. LÄS MER

5. 9. Retinoids and vitamin D in skin and parathyroid glands

   Författare :Liu Wei; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; all-trans retinoic acid 9-cis retinoic acid vitamin A. vitamin D. CRBP. CRABP. RAR. RXR. parathyroid hormone. calcium receptor; Kirurgi; Surgery; Kirurgi; Surgery; kirurgi;

   Sammanfattning : Vitamin D3 (VitD3) and retinoids are important factors involved in differentiation and proliferation in many cell systems. Their effects in skin, where retinoids and vitamin D are known to be crucially involved in keratinocyte differentiation and function,, and in the parathyroid, the overall regulatory organ in calcium homeostasis were studied. LÄS MER

7. 10. Localization and characterization of genes involved in parathyroid tumor development

   Författare :Lars Forsberg; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Parathyroid; Hyperparathyroidsm; MEN1; HRPT2; Menin; Parafibromin; Chromosome 11; Chromosome 1;

   Sammanfattning : The overall goal of this thesis has been to identify new genes and characterize them regarding the involvement in parathyroid tumor development. The parathyroid glands are responsible for the control of calcium homeostasis. Parathyroid tumors usually have a benign growth pattern, with less than 1% of the tumors being malignant. LÄS MER