Sökning: "PWS"

Visar resultat 1 - 5 av 9 avhandlingar innehållade ordet PWS.

  1. 1. Characterisation and treatment of patients with port wine stains with special reference to the emotional impact

    Författare :Agneta Troilius; Dermatologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; capillary malformation; PWS; pulsed dye laser; laser doppler imager; ultrasound; psychosocial impact; depth; reflectance spectrophotometry; Dermatologi; venereologi; venereology; Dermatology;

    Sammanfattning : This thesis covers 12 years of experience in treating patients with congenital capillary malformations, so called port wine stains (PWS). The wide variation in treatment response to laser therapy has developed a profound need for the development of objective devises to measure treatment outcome, so that the maximum effectiveness of therapy can be achieved without unnecessary treatments. LÄS MER

  3. 2. Prader-Willi syndrome : diagnosis and effects of growth hormone treatment

    Författare :Ann Christin Lindgren; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :DNA methylation test; genomic imprinting; glucose intolerance; growth hormone; Prader Willi syndrome; respiratory function;

    Sammanfattning : Prader-Willi syndrome (PWS) is a rare neurogenetic disorder characterised by hypotonia (especially pronounced in the perinatal period) with "failure to thrive", hypogonadism, hypoventilation, dysmorphic features, final short stature and mental retardation. From the age of 2 years hyperphagia develops leading to obesity if the caloric intake is not limited. LÄS MER

  4. 3. Endocrine and metabolic aspects of adult Prader Willi syndrome with special emphasis on the effect of growth hormone treatment

    Författare :Charlotte Höybye; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Prader Willi syndrome; adults; obesity; GH; IGF-I; psycho-social functioning; GH treatment;

    Sammanfattning : Prader Willi Syndrome (PWS) is a complex genetic disorder characterized by muscular hypotonia, hyperphagia, obesity and behavioural problems. Partial growth hormone (GH) deficiency and hypogonadism are common. LÄS MER

  5. 4. Comorbidity and mortality in Prader-Willi syndrome

    Författare :Hasanain Shukur; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Prader-Willi syndrome (PWS) is a multisymptomatic, rare, genetic, disorder, due to lack of the expression of paternal genes in the q11-q13 region of chromosome 15. The main characteristics of PWS are muscular hypotonia, hyperphagia, obesity, behavioral problems, cognitive disabilities, and endocrine deficiencies. LÄS MER

  7. 5. Long-wave ultraviolet radiation (UVA1) and visible light : therapeutic and adverse effects in human skin

    Författare :Desiree Wiegleb Edström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Ultraviolet-A; visible light; p53; p21WAF-1; bcl-2; CD34; port-wine stains; mycosis fungoides; dye laser; photodynamic therapy.;

    Sammanfattning : We studied the effects of repetitive low-dose UVA1 radiation and visible light in normal sunshielded skin, using immunohistochemical staining for p53, p21WAF-1, bcl-2, Ki67 and cyclin A. An increased expression of Ki67 after UVA1 and visible light were observed as a sign of increased proliferation. LÄS MER