Sökning: "mycosis fungoides"

Hittade 3 avhandlingar innehållade orden mycosis fungoides.

  1. 1. Targeted CD52 therapy in lymphoid malignancies : A clinical and immunological study

    Författare :Jeanette Lundin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; CD52; alemtuzumab; Campath; monoclonal antibodies; chronic lymphocytic leukemia; non-Hodgkin s lymphoma; mycosis fungoides; immune suppression;

    Sammanfattning : There is a great need for developing new treatment alternatives in low grade non Hodgkin's lymphoma (NHL) including chronic lymphocytic leukemia (CLL). The CD52 antigen, which is expressed on almost all lymphoid malignancies, can be utilized as a target for CD52-directed monoclonal antibody therapy (alemtuzumab, Campath-1 H). LÄS MER

  2. 2. Long-wave ultraviolet radiation (UVA1) and visible light : Therapeutic and adverse effects in human skin

    Författare :Desiree Wiegleb Edström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; Ultraviolet-A; visible light; p53; p21WAF-1; bcl-2; CD34; port-wine stains; mycosis fungoides; dye laser; photodynamic therapy.;

    Sammanfattning : We studied the effects of repetitive low-dose UVA1 radiation and visible light in normal sunshielded skin, using immunohistochemical staining for p53, p21WAF-1, bcl-2, Ki67 and cyclin A. An increased expression of Ki67 after UVA1 and visible light were observed as a sign of increased proliferation. LÄS MER

  3. 3. Helical tomotherapy for total marrow and total skin irradiation : Optimisation, verification, and clinical results

    Författare :André Änghede Haraldsson; Lund Medicinsk strålningsfysik; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; NATURAL SCIENCES; MEDICAL AND HEALTH SCIENCES; ALL; Leukemia; radiotherapy; hematology; Oncology; Leukemia; radiotherapy; Tomotherapy; Oncology; ALL;

    Sammanfattning : In modern cancer therapy, radiotherapy (RT) is a vital part of most treatments. Most RT treatments in Sweden are performed using intensity-modulated radiotherapy (IMRT) with fixed or dynamic arc delivery. The dose gradients outside the target are steep, the margins are small, and the treatment delivery is complicated. LÄS MER