Sökning: "capillary malformation"

Hittade 5 avhandlingar innehållade orden capillary malformation.

  1. 1. Characterisation and treatment of patients with port wine stains with special reference to the emotional impact

    Författare :Agneta Troilius; Dermatologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; capillary malformation; PWS; pulsed dye laser; laser doppler imager; ultrasound; psychosocial impact; depth; reflectance spectrophotometry; Dermatologi; venereologi; venereology; Dermatology;

    Sammanfattning : This thesis covers 12 years of experience in treating patients with congenital capillary malformations, so called port wine stains (PWS). The wide variation in treatment response to laser therapy has developed a profound need for the development of objective devises to measure treatment outcome, so that the maximum effectiveness of therapy can be achieved without unnecessary treatments. LÄS MER

  3. 2. Cellular and molecular roles for CDC42 in angiogenesis

    Författare :Marco Castro; Christer Betsholtz; Bàrbara Laviña; Rui Benedito; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CDC42; angiogenesis; endothelial cell; vascular malformation; Biology with specialization in Molecular Cell Biology; Biologi med inriktning mot molekylär cellbiologi;

    Sammanfattning : Angiogenesis is the physiological process by which new blood vessels grow and critically depends on the interplay between the major vascular units: endothelial cells, pericytes and smooth muscle cells. Dysfunction and mispatterning of blood vessels are associated with the progression of many vascular complications, and therefore, understanding the causes of vascular dysmorphia is a central question in vascular biology. LÄS MER

  4. 3. FoxF genes in development and disease

    Författare :Seyed Ali Moussavi Nik; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; FOXF1; Sfrp1; LGR5 stem cells; Tgfb; Wnt signaling; ECM; Intact intestinal epithelium; Foxf2; ACDMPV;

    Sammanfattning : Forkhead transcription factors of the FoxF group are important during embryonic de-velopment, and mutation of either of the members, Foxf1 and Foxf2, has fatal conse-quences. In this thesis, I present our recent findings about the mechanism of action of FoxF genes in development and disease. LÄS MER

  5. 4. Cell-autonomous and paracrine mechanisms underlying Pik3ca-driven vascular malformations

    Författare :Milena Petkova; Taija Mäkinen; Ebba Bråkenhielm; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PI3K; PI3KCA; lymphatic malformations; H1047R;

    Sammanfattning : Vascular malformation is a benign overgrowth of blood or lymphatic vessels leading to life-threatening consequences for affected patients. Activating mutations in the TIE2 receptor cause the majority of venous malformations (VMs), while somatic activating mutations in PIK3CA, leading to the overactivation of the PI3K-AKT pathway, cause both VMs and lymphatic malformations (LMs). LÄS MER

  7. 5. Gastroesephageal reflux and related motility disorders after esophageal atresia : a clinical study

    Författare :Madeleine Montgomery; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Esophageal atresia; tracheoesophageal fistula; gastroesophageal reflux; esophageal pH monitoring; respiratory function; gastric emptying; videomanometry STOCKHOLM 1997;

    Sammanfattning : The most common congenital malformation of the esophagus is esophageal atresia (EA) with or without tracheoesophageal fistula (TEF). Successful repair of EA does not ensure normal esophageal function. Disturbed esophageal motility and gastroesophageal reflux (GER) are often detected after repair of EA. LÄS MER