Sökning: "OCS"

Visar resultat 6 - 10 av 31 avhandlingar innehållade ordet OCS.

  1. 6. Molecular studies on the autoantibody-mediated bone destruction in rheumatoid arthritis

    Författare :Akilan Krishnamurthy; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Autoantibody-positive rheumatoid arthritis (RA), also called seropositive RA, is characterised by the presence of anti citrullinated proteins antibodies (ACPA) that can be detected in blood several years before disease onset. Joint inflammation, pain and bone destruction are major features of the disease. LÄS MER

  3. 7. On Observation of and Interaction in Open Distributed Systems

    Författare :Jens-Olof Lindh; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Coherence; interaction; temporal interval; relativity; uncertainty;

    Sammanfattning : The thesis presents the results of research in computer science, as applied within a series of industrial projects. All of these projects have been part of an iterative and adaptive development process, from which we can draw conclusions in three different aspects. LÄS MER

  4. 8. Diagnosing hyper- and hypocortisolism using saliva samples : pitfalls and how to avoid them

    Författare :Nils Bäcklund; Per Dahlqvist; Göran Brattsand; Tommy Olsson; Elisabeth Aardal; Kerstin Landin-Wilhelmsen; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cushing s syndrome; Adrenal Insufficiency; Salivary cortisol; Salivary cortisone; Reference intervals; Diagnostic accuracy; Error sources; invärtesmedicin; Internal Medicine; medicinsk biokemi; Medical Biochemistry;

    Sammanfattning : Background: Cushing's syndrome (CS) is caused by high cortisol secretion whereas insufficient cortisol secretion is called adrenal insufficiency (AI). Both are rare diseases with substantial diagnostic delay, and high morbidity and mortality even though effective treatment is available. LÄS MER

  5. 9. QSBMR Quantitative Structure Biomagnification Relationships : Studies Regarding Persistent Environmental Pollutants in the Baltic Sea Biota

    Författare :Katrin Lundstedt-Enkel; Jan Örberg; Per Larsson; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biology; Biomagnification; Multivariate modelling of environmental data; Transport of contaminants; Environmental toxicology; Biologi; Biology; Biologi;

    Sammanfattning : I have studied persistent environmental pollutants in herring (Clupea harengus), in adult guillemot (Uria aalge) and in guillemot eggs from the Baltic Sea. The studied contaminants were organochlorines (OCs); dichlorodiphenyltrichloroethanes (DDTs), polychlorinated biphenyls (PCBs), hexachlorobenzene (HCB), hexachlorocyclohexanes (HCHs), and brominated flame retardants (BFRs); polybrominated diphenylethers (PBDEs) and hexabromocyclododecane (HBCD). LÄS MER

  7. 10. Significance of Wilms’ tumor gene 1 as a biomarker in acute leukemia and solid tumors

    Författare :Charlotta Andersson; Eva Lundin; Aihong Li; Andreas Jonsson; Xingru Li; David M. Loeb; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Wilms’ tumor gene 1; biomarker; leukemia; renal cell carcinoma; ovarian carcinoma; Clinical Chemistry; klinisk kemi; patologi; Pathology;

    Sammanfattning : Wilms’ tumor gene 1 (WT1) is a zinc finger transcriptional regulator with crucial functions in embryonic development. Originally WT1 was described as a tumor suppressor gene, but later studies have shown oncogenic properties of WT1 in a variety of tumors. Because of its dual functions in tumorigenesis, WT1 has been described as a chameleon gene. LÄS MER