Sökning: "Aihong Li"

Hittade 2 avhandlingar innehållade orden Aihong Li.

1. 1. Wilms' tumor gene 1 in different types of cancer

   Författare :Xingru Li; Aihong Li; Karin Nylander; Eva Lundin; Xiaolian Gu; David M. Loeb; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; WT1; AML; MRD; ccRCC; SNPs; DNA methylation; SCCHN; p63; Clinical Chemistry; klinisk kemi;

   Sammanfattning : The Wilms’ tumor gene 1 (WT1) was first reported as a tumor suppressor gene in Wilms’ tumor. However, later studies have shown the oncogenic properties of WT1 in a variety of tumors. It was recently proposed that WT1 was a chameleon gene, due to its dual functions in tumorigenesis. LÄS MER

3. 2. Significance of Wilms’ tumor gene 1 as a biomarker in acute leukemia and solid tumors

   Författare :Charlotta Andersson; Eva Lundin; Aihong Li; Andreas Jonsson; Xingru Li; David M. Loeb; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Wilms’ tumor gene 1; biomarker; leukemia; renal cell carcinoma; ovarian carcinoma; Clinical Chemistry; klinisk kemi; patologi; Pathology;

   Sammanfattning : Wilms’ tumor gene 1 (WT1) is a zinc finger transcriptional regulator with crucial functions in embryonic development. Originally WT1 was described as a tumor suppressor gene, but later studies have shown oncogenic properties of WT1 in a variety of tumors. Because of its dual functions in tumorigenesis, WT1 has been described as a chameleon gene. LÄS MER