Sökning: "Nuclear pore complex"

Visar resultat 11 - 15 av 35 avhandlingar innehållade orden Nuclear pore complex.

  1. 11. Novel Functionalized Nanopores for Plasmonic Sensing

    Författare :Bita Malekian; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; extinction spectra; nanopores; proteins; nanocaves; nanowells; surface plasmon resonance; nuclear pore complex; colloidal lithography; nanoplasmonic sensor; label-free sensing; electron beam lithography; plasmonic nanostructures;

    Sammanfattning : Nanoplasmonic sensors offer a label-free platform for real-time monitoring of biomolecular interactions by tracking changes in refractive index through optical spectroscopy. However, other surface sensitive techniques such as conventional surface plasmon resonance offer similar capabilities with equal or even better resolution in terms of surface coverage. LÄS MER

  3. 12. The functional organization of nuclear envelope proteins

    Författare :Santhosh Kumar Gudise; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : In eukaryotic cells, the nucleus is enclosed by a double lipid membrane, termed the nuclear envelope (NE). The NE consists of the outer nuclear membrane (ONM), the inner nuclear membrane (INM), the nuclear pore complexes (NPCs) and the nuclear lamina. LÄS MER

  4. 13. Bax and oxidized phospholipids - a deadly complex : Apoptotic protein-lipid assemblies studied by MAS NMR spectroscopy

    Författare :Artur Dingeldein; Gerhard Gröbner; Mikael Elofsson; Tobias Sparrman; Daniel Topgaard; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NMR spectroscopy; mitochondrial membranes; apoptosis; membrane dynamics and organization; Bcl-2 family proteins; Bax protein; biokemi; Biochemistry;

    Sammanfattning : Mitochondria are renowned for their vital role as cellular powerhouses because they provide ATP via cellular respiration. Additionally, these organelles also play an important role in other physiological processes, such as apoptosis. LÄS MER

  5. 14. Temporal events in neuronal differentiation and cell death : expression and processing of the Alzheimer's amyloid precursor protein family and a protein at the nuclear pore

    Författare :Marie Beckman; Kerstin Iverfeldt; David H. Small; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurochemistry; Neurokemi; Neurochemistry and Neurotoxicology; neurokemi och neurotoxikologi;

    Sammanfattning : The present study had two major objectives: 1) to elucidate the involvement of Alzheimer’s amyloid precursor protein (APP) family in neuronal differentiation, and the effect of the Alzheimer’s disease (AD)-linked mutation APPV642I on signal transduction; 2) to investigate the fate of the nuclear pore complex protein POM121 during apoptosis and to examine the possibility of using green fluorescent protein (GFP)-labelled POM121 as a non-invasive sensor of apoptosis in living (non-fixed) cells.APP is the parent protein of the b-amyloid peptide, which is the major peptide constituent in the “senile plaques” of AD. LÄS MER

  7. 15. Structural Investigations of Complex Glasses by Solid-state NMR

    Författare :Ekaterina Leonova; Mattias Edén; Robin Harris; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; glass; glass structure and properties; NMR; magic angle spinning; chemical shift; Physical chemistry; Fysikalisk kemi; Physical Chemistry; fysikalisk kemi;

    Sammanfattning : This PhD thesis presents structural investigations of amorphous inorganic materials: oxide and oxynitride glasses and mesoporous bioactive glasses (MBGs), by solid-state Nuclear Magnetic Resonance (NMR). Lanthanum oxide and oxynitride [La-Si-(Al)-O-(N)] glasses have a large number of potential applications due to their physical properties. LÄS MER