Sökning: "Nuclear DNA"

Visar resultat 26 - 30 av 451 avhandlingar innehållade orden Nuclear DNA.

  1. 26. Epidermal Melanocyte Response to Radiotherapy

    Författare :Per Fessé; Henrik Lindman; Ingela Turesson; Johan Ahlgren; Jan Nyman; Catharine West; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Melanocytes; fractionated radiotherapy; ΔNp63; MITF; PAX3; SOX10; p53; p21; BMI1; pRb; CXCR2; DNA-DSB; 53BP1; CXCR2;

    Sammanfattning : Cutaneous interfollicular melanocytes protect the skin from UV-radiation (UVR), and their response to UVR is well established. To date, the response activated in melanocytes by repeated genotoxic insults from radiotherapy (RT) has not been explored. LÄS MER

  3. 27. The Impact of Tryptase and Epigenetic Mechanisms on Mast Cells

    Författare :Sultan Alanazi; Gunnar Pejler; Constantin Urban; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; mast cells; mastocytosis; tryptase; histone; DNA; methylation; neutrophil extracellular traps; Immunologi; Immunology;

    Sammanfattning : Mast cells have a large influence on multiple immune-mediated responses, including allergic conditions, and they have been implicated in various diseases such as arthritis and cancer. Mastocytosis is characterized by abnormal mast cell proliferation induced by mutations in KIT, the stem cell factor (SCF) receptor. LÄS MER

  4. 28. Nuclear receptor corepressor N-CoR : role in transcriptional repression

    Författare :Kristina Loinder; Mats Söderström; Eckardt Treuter; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : The human body consists of a multitude of cells of varying appearance and function. With a few exceptions they are genetically identical, and the key to their divergence lies in their different specific patterns of gene expression. LÄS MER

  5. 29. Synchrotron radiation studies of gas phase molecules : from hydrogen to DNA sugars

    Författare :Gemma Vall-llosera; Elisabeth Rachlew; Stacey Sorensen; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; KTH thesis; synchrotron radiation; gas phase; bio molecules; Atomic and molecular physics; Atom- och molekylfysik;

    Sammanfattning : This thesis summarises experimental results on the molecular spectroscopy of gas phase molecules excited by synchrotron radiation in the VUV and soft X-ray regions. We have used three different detection techniques, photon induced fluorescence spectroscopy, photoionisation mass spectroscopy and near edge X-ray absorption fine structure spectroscopy to study molecular deuterium, hydrogen sulphide, ammonia, methanol, pyridine, pyridazine, pyrimidine, pyrazine, s-triazine, and 2-deoxy-D-ribose, the last one also known as the DNA sugar. LÄS MER

  7. 30. Climbing the Trichoptera Tree : Investigations of Branches and Leaves

    Författare :Tobias Malm; Kjell Arne Johanson; Wolfram Mey; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Trichoptera; Leptoceridae; Symphitoneuria; Gracilipsodes; Triplectides; morphology; DNA; systematics; phylogeny; New Caledonia; Madagascar; new species; new genus; Systematics and phylogenetics; Systematik och fylogeni; Systematic Zoology; zoologisk systematik och evolutionsforskning;

    Sammanfattning : The Trichoptera (caddisflies) is the largest of the primary aquatic insect orders, currently including more than 13,500 species. With more than 100 species new to science described annually, the known caddisfly diversity is rapidly increasing. In the first four papers of this Thesis, a total of 22 species new to science are described. LÄS MER