Sökning: "Nuclear DNA"

Visar resultat 16 - 20 av 451 avhandlingar innehållade orden Nuclear DNA.

  1. 16. Herpes Simplex Virus 1 DNA replication and its role in recombination and transcription

    Författare :Ka-Wei Tang; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Herpes Simplex Virus 1; DNA replication; DNA recombination; Transcription;

    Sammanfattning : Herpes simplex virus 1 (HSV-1) is one of nine different herpesvirus infecting man. They are all capable of establishing a life-long latent state following the primary infection. HSV-1 as well as other herpesviruses may reactivate from the latent state and give rise to a productive infection with clinical symptoms or asymptomatic shedding. LÄS MER

  3. 17. Functional studies of nuclear envelope-associated proteins in Saccharomyces cerevisiae

    Författare :Ida Olsson; Ann Mutvei; Valérie Doye; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Nucleus; nuclear envelope; nuclear pore complexes; vesicular traffic; arginine methylation; Rmt2; Cwh43; Myr1; Biochemistry; Biokemi; biokemi; Biochemistry;

    Sammanfattning : Proteins of the nuclear envelope play important roles in a variety of cellular processes e.g. transport of proteins between the nucleus and cytoplasm, co-ordination of nuclear and cytoplasmic events, anchoring of chromatin to the nuclear periphery and regulation of transcription. LÄS MER

  4. 18. Modelling the Protein-DNA Interface

    Författare :Malin Lüking; Shina C. Lynn Kamerlin; Ehmke Pohl; Uppsala universitet; []
    Nyckelord :Protein-DNA interactions; Molecular Dynamics; Coarse-grained simulations; gene regulation; Biokemi; Biochemistry;

    Sammanfattning : Protein-DNA interactions are crucial to life. Several millions of DNA base pair steps are organ- ised, read and protected by proteins in every cell. Protein-DNA interactions must be specific, controllable and reasonably fast. Understanding how these features coexist is one of the great challenges for biochemists and molecular biologists. LÄS MER

  5. 19. Studies on nuclear factor 1 binding to nucleosomal DNA

    Författare :Patrik Blomquist; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :nuclear factor 1; nucleosome; glucocorticoid receptor; triplex DNA; the SWISNF complex; A-tracts; MMTV LTR;

    Sammanfattning : The organisation of DNA into chromatin will influence on transcriptional regulation. The first event in transcriptional activation is the binding of transcription factors to specific binding sites in the regulatory regions of the gene. LÄS MER

  7. 20. Thermodynamics of protein-DNA interactions

    Författare :Thomas Lundbäck; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :DNA-protein interactions; molecular recognition; thermodynamics; specificity.dehydration; salt dependence.;

    Sammanfattning : This thesis treats the molecular recognition between DNA-binding proteins and DNA and the way these interactions are affected by the surrounding water solution and dissolved solutes. The work involves studies on the thermodynamics of sequence specific DNA-binding of the human glucocorticoid receptor DNA-binding domain and the nonsequence specific DNA- binding of Sso7d from the archaeon Sulfolobus solfataricus. LÄS MER