Sökning: "Nuclear envelope proteins"

Visar resultat 1 - 5 av 35 avhandlingar innehållade orden Nuclear envelope proteins.

1. 1. Nuclear envelope protein interaction studies

   Författare :Mohammed Hakim Jaffer Ali; Einar Hallberg; Anki Östlund-Farrants; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Samp1; Nuclear envelope; protein interactions; chemical crosslinking; proteomics; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

   Sammanfattning : The nuclear envelope (NE) separating the nucleoplasm from cytoplasm consists of two concentric lipid membranes, the outer (ONM) and inner (INM) nuclear membranes, the nuclear pore complexes (NPCs) and an underlying nuclear lamina network. The INM contains more than 100 unique transmembrane proteins of which only a few have been characterized. LÄS MER

3. 2. Functional studies of nuclear envelope-associated proteins in Saccharomyces cerevisiae

   Författare :Ida Olsson; Ann Mutvei; Valérie Doye; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Nucleus; nuclear envelope; nuclear pore complexes; vesicular traffic; arginine methylation; Rmt2; Cwh43; Myr1; Biochemistry; Biokemi; biokemi; Biochemistry;

   Sammanfattning : Proteins of the nuclear envelope play important roles in a variety of cellular processes e.g. transport of proteins between the nucleus and cytoplasm, co-ordination of nuclear and cytoplasmic events, anchoring of chromatin to the nuclear periphery and regulation of transcription. LÄS MER

4. 3. Identification and characterization of nuclear envelope protein interactions

   Författare :Balaje Vijayaraghavan; Einar Hallberg; Ing-Marie Nilsson; Bengt Mannervik; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Samp1; MCLIP; Nuclear envelope; Ran; Emerin; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

   Sammanfattning : The Nuclear envelope which surrounds the chromatin of eukaryotic cells contains more than a hundred transmembrane proteins. Mutations in some genes encoding nuclear envelope proteins give rise to human diseases including neurological disorders. The function of many nuclear envelope proteins is not well established. LÄS MER

5. 4. The role of nuclear envelope proteins in chromatin organization, differentiation and disease

   Författare :Cecilia Bergqvist; Einar Hallberg; Philippe Collas; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Nuclear envelope proteins; chromatin organization; epigenetics; differentiation; quantitative image analysis; Samp1; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

   Sammanfattning : In eukaryotes the genetic material is separated from the cytoplasm by the nuclear envelope (NE), consisting of the outer and inner nuclear membrane, the nuclear lamina and the nuclear pores. The genetic material is highly structured with transcriptionally inactive heterochromatin enriched at the nuclear periphery and transcriptionally active euchromatin in the nuclear interior. LÄS MER

7. 5. Identification and characterization of protein-protein interactions in the nuclear envelope

   Författare :Balaje Vijayaraghavan; Einar Hallberg; Katherine Wilson; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Nuclear envelope; Samp1; Emerin; Ran and transmembrane proteins; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

   Sammanfattning : The nuclear envelope forms the interface between the nucleus and the cytoplasm. The nuclear envelope consists of the two concentric lipid membranes, the nuclear pores and the nuclear lamina. The inner nuclear membrane contains hundreds of unique transmembrane proteins showing high tissue diversity. LÄS MER