Sökning: "mastocytosis"

Visar resultat 1 - 5 av 8 avhandlingar innehållade ordet mastocytosis.

  1. 1. Signal Transduction in Mast Cell Migration

    Författare :Magnus Sundström; Bengt Hallberg; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; HMC-1; Kit; MAP kinase; mast cells; mastocytosis; p38; SCF; TGF-β; Genetik; Clinical genetics; Klinisk genetik; Pathology; patologi;

    Sammanfattning : Mast cells are essential effector cells in the immune system as they release several inflammatory mediators. An accumulation of mast cells has been described in inflammatory conditions such as asthma and allergic rhinitis. LÄS MER

  3. 2. The Impact of Tryptase and Epigenetic Mechanisms on Mast Cells

    Författare :Sultan Alanazi; Gunnar Pejler; Constantin Urban; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; mast cells; mastocytosis; tryptase; histone; DNA; methylation; neutrophil extracellular traps; Immunologi; Immunology;

    Sammanfattning : Mast cells have a large influence on multiple immune-mediated responses, including allergic conditions, and they have been implicated in various diseases such as arthritis and cancer. Mastocytosis is characterized by abnormal mast cell proliferation induced by mutations in KIT, the stem cell factor (SCF) receptor. LÄS MER

  4. 3. Mast cell development in health and systemic mastocytosis

    Författare :Jennine Grootens; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Hematopoietic progenitors in the bone marrow differentiate into several immune cells, including mast cells. Mast cell progenitors leave the bone marrow, circulate through the blood, and home to the periphery where they mature. LÄS MER

  5. 4. Charting mast cell development in health and systemic mastocytosis

    Författare :Chenyan Wu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Hematopoietic stem and progenitor cells give rise to various blood and immune cells, including mast cells. In adults, bone marrow hematopoietic stem cells give rise to mast cell progenitors. These mast cell progenitors circulate in the peripheral blood and mature in peripheral tissues. LÄS MER

  7. 5. Mast cell activation disorders : a liaison between anaphylaxis and mastocytosis

    Författare :Theo Gülen; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The term mast cell activation disorders (MCAD) comprises a broad spectrum of heterogeneous conditions, such as mastocytosis, characterized by inappropriate mast cell activation/accumulation. The patients present with protean clinical manifestations and severity grade of symptoms may vary from case-to-case. LÄS MER