Sökning: "Nicotinic acetylcholine receptor"

Visar resultat 6 - 10 av 55 avhandlingar innehållade orden Nicotinic acetylcholine receptor.

  1. 6. Aspects of Non-Neuronal Signalling Functions of Acetylcholine in Colorectal Cancer : Roles for the α7nAChR

    Författare :Ann Novotny; Dick Delbro; Eva Ekblad; Högskolan i Kalmar; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; alpha7 nicotinic acetylcholine receptor; acetylcholine; colorectal cancer; morphine; nicotine; plasminogen activator inhibitor-1; SLURP-1; Oncology; Onkologi; Biomedical Sciences; Biomedicinsk vetenskap;

    Sammanfattning : .... LÄS MER

  3. 7. The role of the alpha 7 nicotinic acetylcholine receptor in inflammation and brain injury

    Författare :Maria Hammarlund; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; alpha 7 nicotinic acetylcholine receptor; inflammation; brain injury; CHRNA7; CHRFAM7A; stroke; hypoxia ischemia; neonatal encephalopathy; human; PBMC;

    Sammanfattning : The alpha 7 nicotinic acetylcholine receptors (α7nAChR) are expressed in the nervous system as well as on peripheral immune cells where it participates in the cholinergic anti-inflammatory pathway. Inflammation is a common component in the pathology of many diseases and injuries, including brain damage. LÄS MER

  4. 8. Conditional and non-conditional reward-related responses to alcohol. Nicotinic mechanisms

    Författare :Elin Löf; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ethanol; nicotine; ventral tegmental area; nucleus accumbens; dopamine; nicotinic acetylcholine receptor; gamma-amino-butyric acid receptor A; conditioned reinforcement; in vivo microdialysis; rat;

    Sammanfattning : The mesolimbic dopamine system is believed to mediate the positive reinforcing and rewarding effects of addictive drugs by increasing dopamine levels in its terminal area, the nucleus accumbens (nAc). Nicotinic acetylcholine receptors (nAChRs) within this system appear important for the pharmacological actions of both alcohol and nicotine, which may explain the frequent co-abuse of these two drugs. LÄS MER

  5. 9. Advanced Fluorescence Microscopy to Study Plasma Membrane Protein Dynamics

    Författare :Joachim Piguet; Horst Vogel; Ruud Hovius; Jerker Widengren; Antoine Triller; Switzerland Ecole Polytechnique Fédérale de Lausanne (EPFL); []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; fluorescence; microscopy; plasma membrane; membrane proteins; membrane proteins diffusion; single-molecule imaging; single-molecule tracking; pentameric ligand-gated ion channels; nicotinic acetylcholine receptor; serotonin receptor; synapse; neuromuscular junction; post-synaptic scaffold; rapsyn; myopathies; fluorescent proteins; Förster resonance energy transfer; FRET imaging; protein-protein interactions; protein trafficking; photo-activatable proteins; Biological Physics; Biologisk fysik;

    Sammanfattning : Membrane protein dynamics is of great importance for living organisms. The precise localization of proteins composing a synapse on the membrane facing a nerve terminus is essential for proper functioning of the nervous system. In muscle fibers, the nicotinic acetylcholine is densely packed under the motor nerve termini. LÄS MER

  7. 10. Biochemical and immunological characterization of the nicotinic acetylcholine receptor from Torpedo marmorata electric organ

    Författare :Lena Elfman; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Neuronal information transfer in vertebrate skeletal muscle and in the electric organ of e.g. Torpedo is mediated by acetylcholine (ACh). The nicotinic acetylcholine receptor (nAChR) complex translates the binding of ACh into permeability changes. LÄS MER