Sökning: "Mesenchymal stem cell"
Visar resultat 16 - 20 av 120 avhandlingar innehållade orden Mesenchymal stem cell.
16. The osteogenic potential of human mesenchymal stem cells: Novel markers and key factors for differentiation
Sammanfattning : Mesenchymal stem cells are multipotent stem cells with ability to differentiate into cells of the connective tissue lineage, such as adipocytes, osteoblasts and chondrocytes, both in vitro and in vivo. The main objective of the present thesis was to study different aspects of the osteogenic potential of MSCs. LÄS MER
17. Mesenchymal Stem Cells in Tumor Growth Inhibition and Cartilage Differentiation
Sammanfattning : The work presented in this thesis has been focused on mesenchymal stem cells (MSCs). In the two first studies, the effects of MSCs on tumor growth and development in vitro and in vivo was investigated. LÄS MER
18. The role of hyaluronan and its CD44 receptor in inflammation and cancer
Sammanfattning : Hyaluronan, an important extra-cellular matrix molecule, was thought to be interstitial connecting glue decades ago. However, recent evidence has revealed that hyaluronan and its binding proteins also play crucial roles in various pathophysiological conditions in humans, including inflammation and infection. LÄS MER
19. Adenovirus for Cancer Therapy : With a Focus on its Surface Modification
Sammanfattning : Adenovirus serotype 5 (Ad5) is widely used as an oncolytic agent for cancer therapy. However, its infectivity is highly dependent on the expression level of coxsackievirus-adenovirus receptor (CAR) on the surface of tumor cells. LÄS MER
20. Human embryonic stem cells for bone engineering applications
Sammanfattning : The human skeleton represents the supporting structure of the organism and accounts for about 20 percent of the total body mass. Despite its intrinsic capacity to regenerate and self-repair, this ability is limited and repair therapies are needed in a large number of clinical cases. LÄS MER