Sökning: "Mesenchymal stem cell"

Visar resultat 6 - 10 av 120 avhandlingar innehållade orden Mesenchymal stem cell.

1. 6. Challenges in Islet Transplantation and Strategies to Improve Beta-Cell Function

   Författare :Hanna Liljebäck; Per-Ola Carlsson; James Shaw; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Islet transplantation; Type 1 diabetes; Mesenchymal stem cells; Medical Cell Biology; Medicinsk cellbiologi;

   Sammanfattning : The incidence of type 1 diabetes is increasing worldwide and therapies of islet transplantation and potential cell-based therapies are rapidly evolving. Choosing the optimal site for such therapies is crucial for safety and for obtaining the best possible outcome. LÄS MER

3. 7. Mesenchymal stromal cells in malignant glioma - Functions and therapeutic potential

   Författare :Andreas Svensson; Neurokirurgi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; glioma; glioblastoma; mesenchymal stromal cell; pericyte; immunotherapy; interferon-γ;

   Sammanfattning : The most common malignant brain tumor in adults is a glioma called glioblastoma multiforme (GBM). About 300 persons are diagnosed with GBM every year in Sweden. Unfortunately, it is also the most aggressive brain tumor and as of today, it is not possible to cure it. LÄS MER

4. 8. The Role of Microvascular Pericytes in the Generation of Pro-fibrotic Connective Tissue Cells : Investigations in vitro and in Reactive Tissues in vivo

   Författare :Jakob Karén; Christian Sundberg; Gunilla Westergren-Thorsson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pericyte fibroblast differentiation fibrosis; Biochemistry; Biokemi; Microbiology; Mikrobiologi; Cell biology; Cellbiologi; Medical Biochemistry; Medicinsk biokemi; Cellforskning; Cell Research; Mikrobiologi; Microbiology;

   Sammanfattning : Pericytes are cells of mesenchymal origin located on the abluminal side, juxtapositioned to the endothelial cells in capillaries, venules and small arterioles. They are important for maintaining vessel integrity in resting tissues as well as the formation and stabilization of new vessels. LÄS MER

5. 9. Dental mesenchymal stem cells

   Författare :Nina Kaukua; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Mesenchymal stem cells have been found in various tissues and act as source for renewal and repair. The mouse incisor tooth continuously grows throughout life, implicating that there are stem cell niches constantly contributing with cells. The composition of these stem cell niches is not fully understood. LÄS MER

7. 10. Development of biosynthetic conduits for peripheral nerve repair

   Författare :Aleksandra McGrath; Liudmila N Novikova; John Haycock; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biosynthetic conduit; Mesenchymal stem cells; Nerve graft; Nerve tissue engineering; Peripheral nerve injury; Schwann cells;

   Sammanfattning : Peripheral nerve injuries are often associated with significant loss of nervous tissue leading to poor restoration of function following repair of injured nerves. Although the injury gap could be bridged by autologous nerve graft, the limited access to donor material and additional morbidity such as loss of sensation and scarring have prompted a search for biosynthetic nerve transplants. LÄS MER