Sökning: "Medicinsk vetenskap"
Visar resultat 6 - 10 av 387 avhandlingar innehållade orden Medicinsk vetenskap.
6. Development of a Cancer Vaccine Targeting Tumor Blood Vessels
Sammanfattning : A treatment strategy for cancer is the suppression of tumor growth by directing an immune response to the tumor vessels, which will destroy the tissue.In this thesis we describe the development of a vaccine that targets antigens expressed around angiogenic vasculature in most solid tumors. LÄS MER
7. Responses of bovine endometrial epithelial cells to pathogens
Sammanfattning : In dairy cows, clinical uterine infection (metritis) and subsequent persistent inflammation of the endometrium (endometritis) are major causes of infertility. Escherichia coli (E. LÄS MER
8. Extracellular Matrix and Connective Tissue Cells of the Tumor Microenvironment
Sammanfattning : In addition to malignant cells, solid tumors comprise supporting stromal tissue that consists of extra cellular matrix (ECM), connective tissue cells, inflammatory cells and blood vessels. The stromal compartment and the malignant cells together shape the tumor microenvironment that in turn determines tumor progression and efficacy of anti-tumor treatments. LÄS MER
9. High-throughput screening using multicellular tumor spheroids to reveal and exploit tumor-specific vulnerabilities
Sammanfattning : High-throughput drug screening (HTS) in live cells is often a vital part of the preclinical anticancer drug discovery process. So far, two-dimensional (2D) monolayer cell cultures have been the most prevalent model in HTS endeavors. However, 2D cell cultures often fail to recapitulate the complex microenvironments of in vivo tumors. LÄS MER
10. Studies of the molecular genetics and epidemiology of porcine rubulavirus infection
Sammanfattning : Porcine rubulavirus (PorPV) infection emerged spontaneously in pigs in Mexico in the early 1980s. Since the report of the initial outbreak of the disease, only one full-length genome from a strain isolated in 1984 (PorPV-LPMV/1984) has been sequenced. There is therefore limited information about the genetic variation of this virus. LÄS MER