Sökning: "Lymph Nodes immunology"

Visar resultat 6 - 10 av 34 avhandlingar innehållade orden Lymph Nodes immunology.

  1. 6. Cancer Immunotherapy : Evolving Oncolytic viruses and CAR T-cells

    Författare :Mohanraj Ramachandran; Magnus Essand; Di Yu; Justyna Leja-Jarblad; Richard Vile; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncolytic virus; Adenovirus; Semliki Forest virus; Cancer immunology; Chimeric antigen receptor T-cells; Immunologi; Immunology; Oncology; Onkologi; Biology with specialization in Molecular Biotechnology; Biologi med inriktning mot molekylär bioteknik;

    Sammanfattning : In the last decade cancer immunotherapy has taken huge strides forward from bench to bedside and being approved as drugs. Cancer immunotherapy harnesses the power of patient’s own immune system to fight cancer. LÄS MER

  3. 7. Reduced ROS production triggers arthritis / The role of T cells in arthritis pathogenesis

    Författare :Jens Holmberg; Immunologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; transplantation; Spleen and lymph nodes Inflammation Reactive oxygen species T cells MHC; serology; Immunology; Immunologi; serologi;

    Sammanfattning : The aim of this thesis is to defend a novel mechanism that triggers arthritis susceptibility in both rats and mice through reduced production of reactive oxygen species (ROS), but also to introduce a novel model for chronic relapsing arthritis. Five papers are included, all of which employ animal models for rheumatoid arthritis and one that also uses animal models for multiple sclerosis. LÄS MER

  4. 8. Chemokine Receptor CCR9: Studies on the Generation and Localization of Gut Tropic Lymphocytes

    Författare :Marcus Svensson Frej; Immunologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; small intestine; transplantation; serologi; CCR9; CCL25; chemokines; lymphocyte homing; Immunology; serology; Immunologi;

    Sammanfattning : Lymphocytes are important mediators of adaptive immune responses. Naive T lymphocytes circulate in the blood and lymph between different secondary lymphoid organs in search for their specific antigen. LÄS MER

  5. 9. Dendritic cells and Plasmodium falciparum: studies in vitro and in the human host

    Författare :Pablo Giusti; Marita Troye-Blomberg; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; Immunologi; immunologi; Immunology;

    Sammanfattning : Malaria is one of the world’s most threatening diseases. About half the world’s population is at risk of infection and the infection claims a million lives each year. A vast majority of the deaths occur in children below the age of 5 in sub-Saharan Africa. LÄS MER

  7. 10. T Regulatory Cells – Friends or Foes?

    Författare :Camilla Lindqvist; Angelica Loskog; Thomas Tötterman; Vivianne Malmström; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Treg; T regulatory cell; FoxP3; CD25; CLL; B-cell lymphoma; Clinical immunology; Klinisk immunologi; Klinisk immunologi; Clinical Immunology;

    Sammanfattning : T regulatory cells (Tregs) have been extensively studied in patients with cancer or autoimmunity. These cells hamper the immune system’s ability to clear tumor cells in cancer patients. In autoimmune diseases, on the other hand, they are not able to restrain autoreactive immune responses. LÄS MER