Sökning: "Leukocyte and platelet recruitment"

Visar resultat 1 - 5 av 11 avhandlingar innehållade orden Leukocyte and platelet recruitment.

1. 1. Platelet-dependent pulmonary recruitment of neutrophils in abdominal sepsis

   Författare :Milladur Rahman; Kirurgi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; abdominal sepsis; neutrophil recruitment; platelet; lung injury;

   Sammanfattning : Sepsis and subsequent multiple organ failure remain the major cause of mortality in intensive care units. Leukocyte-mediated tissue damage is a key feature in septic lung injury. Accumulating data suggest that platelets play a role in inflammation and tissue injury. LÄS MER

3. 2. Microcirculation, Mucus and Microbiota in Inflammatory Bowel Disease

   Författare :Olof Schreiber; Lena Holm; Mia Phillipson; Henrik Sjövall; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; inflammatory bowel diseases; experimental colitis; DSS; TNBS; colonic mucosal blood flow; laser-doppler flowmetry; colonic mucus thickness; MUC2; colonic mucosal barrier function; iNOS; eNOS; probiotics; Lactobacilli; Lactobacillus reuteri; colonic microbiota; T-RFLP; bacterial translocation; intravital microscopy; P-selectin; leukocyte recruitment; platelet recruitment; Physiology; Fysiologi; Physiology; Fysiologi;

   Sammanfattning : Inflammatory bowel diseases, (IBD), are a group of chronic disorders of the gastro-intestinal tract, and include Crohn’s disease (CD) and Ulcerative Colitis (UC). The pathogenesis is not known, but involves at least in part a loss of tolerance towards the commensal colonic microbiota. LÄS MER

4. 3. On Leukocyte Recruitment in Cholestatic Liver Injury

   Författare :Matthias Laschke; Kirurgi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Leukocyte and Liver; Inflammation; Cholestasis; Endothelium;

   Sammanfattning : Cholestasis is a frequent clinical syndrome, which is caused by a dysfunction in bile formation of the hepatocyte or from obstruction of the biliary tract. This is associated with inflammation of the liver tissue, resulting in severe liver injury. In this inflammatory process, leukocyte recruitment has emerged as a key feature. LÄS MER

5. 4. Intestinal ischemia and reperfusion. Proinflammatory response and organ dysfunction

   Författare :Knut Olanders; Lund Institutionen för kliniska vetenskaper; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; traumatology; Kirurgi; ortopedi; traumatologi; orthopaedics; Surgery; inflammation; cytokine; leukocyte; reperfusion; ischemia; permeability; Intestine; endothelium;

   Sammanfattning : Intestinal I/R is considered to be an important initiating event in several pathophysiological conditions such as trauma, bleeding, sepsis and pancreatitis, frequently leading to concomitant both single and potentially multiple organ dysfunction. The purpose of this thesis was to study mechanims underlying the development of multiple organ dysfunction, with special focus on intercellular proinflammatory regulation in the concurrent development of tissue injury. LÄS MER

7. 5. On Microvascular Inflammation and Intestinal Leakage in Radiation Enteropathy

   Författare :Andrada Röme; Kirurgi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; radiation; colon; intestinal leakage; Leukocyte and platelet recruitment;

   Sammanfattning : Gastrointestinal tract damage is an insidious feature in patients undergoing radiotherapy. Microvascular inflammation, including leukocyte and platelet recruitment as well as epithelial barrier dysfunction, are considered to constitute key components in the pathophysiology of radiation-induced enteropathy. LÄS MER