Sökning: "MUC2"

Visar resultat 1 - 5 av 22 avhandlingar innehållade ordet MUC2.

  1. 1. Intestinal mucins 'soluble and insoluble problems'

    Författare :Annkatrin Herrmann; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; colorectal carcinoma; pulse labelling; organ culture; glycopeptide; small intestine; colon; glycoprotein complex; insoluble; muc2; MUC2; Mucin; mucus; carbohydrate; oligosaccharide.; Gastro-enterology; Gastroenterologi;

    Sammanfattning : Highly glycosylated glycoproteins – mucins – are the major constituents of the mucus layer and glycocalyx that cover mucosal surfaces. Twelve human mucin genes have been identified, and the mucins may be divided into those that are membraneassociated and those that are secreted. LÄS MER

  2. 2. The MUC2 mucin -A network in the intestinal protective mucus

    Författare :Malin E V Johansson; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :mucus; Muc2; trimer; proteomics; intestine; colitis; DSS;

    Sammanfattning : The intestine is covered by mucus that is the first line of defence of the epithelium. The main structural component of the intestinal mucus is the MUC2 mucin. This is a large glycoprotein with two long and heavily O-glycosylated mucin domains. LÄS MER

  3. 3. Study of the colonic mucus layer by mass spectrometry

    Författare :Sjoerd van der Post; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MUC2; mucin; intestine; proteomics; mass spectrometry;

    Sammanfattning : The mucus covering our internal mucosal surfaces is a part of the innate immune system, and the first line of defense against microbial challenges. The need of an efficient defense system is especially important in the lower parts of the digestive tract where the microbiota reaches its highest density. LÄS MER

  4. 4. Assembly and proteolytic cleavages of gel-forming mucins

    Författare :Martin Lidell; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :mucins; MUC2; MUC5AC; dimer; trimer; cleavage; Entamoeba histolytica; cysteine protease;

    Sammanfattning : Gel-forming mucins are large glycoproteins constituting the main structural component of themucus layer protecting epithelial surfaces of the body. This thesis aims to a deeper understandingof how gel-forming mucins are synthesized and assembled, and how they may interact with othermolecules. LÄS MER

  5. 5. Mucus associated proteins and their functional role in the distal intestine

    Författare :Joakim H. Bergström; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; intestine; mucus; bacteria; MUC2; AGR2; FCGBP; ZG16;

    Sammanfattning : The mammalian intestine, especially the large intestine, harbors complex societies of beneficial bacteria coexisting with the host. This is a mutualistic relationship, where the host provides nutrients and a favorable environment while the bacteria in return ferment indigestible polysaccharides to short chain fatty acids. LÄS MER