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Visar resultat 1 - 5 av 11 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Identification and Characterization of Proteins and MicroRNAs that Modulate Receptor Signaling, Vesicular Trafficking and Cell Migration in Vascular Cells

   Författare :Johan Heldin; Johan Kreuger; Jonas Fuxe; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Angiogenesis; cell migration; signaling; VEGF; FGD5; ExoC3L2; microRNA; RhoD; Molekylär cellbiologi; Molecular Cellbiology;

   Sammanfattning : Blood vessels deliver nutrients and oxygen to tissues. Importantly, the functions and growth of blood vessels are commonly altered in disease. The inside of all blood vessels are lined with endothelium, a thin specialized layer of endothelial cells that separate the blood from other tissues. LÄS MER

3. 2. De probatione causarum judiciali in genere nec non de probiatione causarum indirecta dissertatio academica. Quam ... p. p. Johannes Christoph. Lindblad ... et Johannes Christ. Kreüger Holmiensis. In audit. Gustav. die XXV Maji MDCCCXLII h. a. m. s., P. I

   Författare :Johan Christofer Lindblad; Joh. Christ. Kreüger; Johan Christofer Lindblad; Uppsala universitet; []
   Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES;

   Sammanfattning : .... LÄS MER

4. 3. Decoding Heparan Sulfate

   Författare :Johan Kreuger; John T. Gallager; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Heparan sulfate; fibroblast growth factor; receptor; endostatin; angiogenesis; interaction; sequence; Biokemi; Biochemistry; Biokemi; Medical Biochemistry; medicinsk biokemi;

   Sammanfattning : Heparan sulfate (HS) is a polysaccharide of glycosaminoglycan type composed of alternating hexuronic acid [either glucuronic acid (GlcA) or iduronic acid (IdoA)] and glucosamine (GlcN) units that can be sulfated in various positions. HS binds to a large number of proteins and these interactions promote many biological processes, including cell adhesion and growth factor signaling. LÄS MER

5. 4. Exploring Cellular Dynamics : From Vesicle Tethering to Cell Migration

   Författare :Parham Ashrafzadeh; Johan Kreuger; Jonas Fuxe; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; angiogenesis; cancer; cell migration; exocyst complex; exocytosis; FGD5; lipid rafts; plasma membrane; receptor trafficking; VEGFR2;

   Sammanfattning : Cells in the body communicate with each other in order to cooperate efficiently. This communication is in part achieved by regulated secretion of signaling molecules, which when released from a cell may activate receptors present at the plasma membrane of an adjacent cell. Such signals affect both cell fate and behavior. LÄS MER

7. 5. Directing Angiogenesis : Cellular Responses to Gradients in vitro

   Författare :Irmeli Barkefors; Johan Kreuger; Lena Kjellén; Pär Gerwins; Ferdinand Le Noble; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Angiogenesis; Endothelial cell; Cell migration; Chemotaxis; Gradients; Microfluidics; VEGFA; VEGFR2; Exocyst; Exocytosis; Cell and molecular biology; Cell- och molekylärbiologi; Medical Biochemistry; Medicinsk biokemi;

   Sammanfattning : Blood vessels are essential for the delivery of nutrients and oxygen to tissues, as well as for the removal of waste products. Patients with tumors, wounds or diabetes all have active angiogenesis, formation and remodeling of blood vessels, a process that is initiated and manipulated by gradients of secreted signaling proteins. LÄS MER