Sökning: "Herpes virus type 2"
Visar resultat 6 - 10 av 38 avhandlingar innehållade orden Herpes virus type 2.
6. Immune regulation of herpes simplex virus type 2 infection: Special emphasis on the transcription factor T-bet
Sammanfattning : Herpes simplex virus type 2 (HSV-2) is a sexually transmitted pathogen that infects the genital tract mucosa as well as local sensory neurons. It is the most common cause of genital ulcer disease in humans. The infection gives rise to a wide range of symptoms, ranging from severe and painful recurrent episodes of genital herpes to silent infection. LÄS MER
7. The discovery of antiviral compounds targeting adenovirus and herpes simplex virus : assessment of synthetic compounds and natural products
Sammanfattning : There is a need for new antiviral drugs. Especially for the treatment of adenovirus infections, since no approved anti-adenoviral drugs are available. Adenovirus infections in healthy persons are most often associated with respiratory disease, diarrhea and infections of the eye. These infections can be severe, but are most often self-limiting. LÄS MER
8. Anti-herpes simplex virus activities of sulfomannan oligosaccharide PI-88 and disulfated cyclitols
Sammanfattning : Herpes simplex virus (HSV) initiates invasion of human cells by binding to the cell surface heparan sulfate (HS) glycosaminoglycan chains. This step is mediated by the viral envelope glycoproteins gC and/or gB. LÄS MER
9. Interaction of herpes simplex virus with cell surface glycosaminoglycans as a target for antiviral intervention
Sammanfattning : Herpes simplex virus (HSV) infections in humans are predominantly manifested as oral cold sores or genital ulcers. As HSV infects cells by interaction with cell surface heparan sulfate (HS) and/or chondroitin sulfate (CS), the aim of the research work presented in this thesis was to explore the possibility of antiviral intervention with compounds that mimic HS or CS. LÄS MER
10. Sexually transmitted infections: serological, microbiological and microscopical aspects
Sammanfattning : The prevalence of sexually transmitted infections (STI) is high in the adult populations world-wide but varies between populations and time periods. Since a high proportion of infected individuals are asymptomatic, diagnostic approaches to reduce further transmission and complications are essential. LÄS MER