Sökning: "Good manufacturing practice GMP"
Hittade 5 avhandlingar innehållade orden Good manufacturing practice GMP.
1. The therapeutic potential of ex vivo expanded natural killer (NK) cells for immunotherapy of cancer
Sammanfattning : Cell and gene therapy of cancers has received much attention in the past decade. A number of applications of cancer treatment have been developed and used. One of the recent applications is immunotherapy of tumours with human natural killer (NK) cells. LÄS MER
2. Method development for [11C]carbon monoxide radiochemistry
Sammanfattning : Positron emission tomography (PET) is a non-invasive molecular imaging technique that has found extensive utility in biomedical research and in drug development. A fundamental pre-requisite for PET is the tracer, which is a biologically relevant molecule, labeled with a short-lived radionuclide. LÄS MER
3. Development and optimization of a 3D in vitro model for osteogenic biomaterial evaluation
Sammanfattning : Despite the innate regenerative capabilities of bone tissue, self-repair is impaired when an injury exceeds the critical size threshold because of trauma, congenital, or pathological conditions. Autologous transplantation is the gold standard to reconstruct large bone defects. LÄS MER
4. Keratinocytes and Adipose-derived mesenchymal stem cells : The heir and the spare to regenerative cellular therapies for difficult-to-heal skin wounds
Sammanfattning : Cell-based therapy is considered as Advanced Therapy Medicinal Product, (ATMP), which had increasingly stricter regulations in the last decade. The cells must be produced according to the ‘Guidelines on Good Manufacturing Practice (GMP) specific to Advanced Therapy Medicinal Products’, adopted by the European Medicines Agency (EMA). LÄS MER
5. Targeting innate and adaptive immune responses to achieve long-term allograft acceptance following transplantation
Sammanfattning : Organ transplantation outcomes have gradually improved over the last 50 years. The development of more effective immunosuppressive drugs has been a major contributor to this improvement. LÄS MER