Sökning: "Keratinocytes"
Visar resultat 1 - 5 av 113 avhandlingar innehållade ordet Keratinocytes.
1. Keratinocytes and Adipose-derived mesenchymal stem cells : The heir and the spare to regenerative cellular therapies for difficult-to-heal skin wounds
Sammanfattning : Cell-based therapy is considered as Advanced Therapy Medicinal Product, (ATMP), which had increasingly stricter regulations in the last decade. The cells must be produced according to the ‘Guidelines on Good Manufacturing Practice (GMP) specific to Advanced Therapy Medicinal Products’, adopted by the European Medicines Agency (EMA). LÄS MER
2. Epidermal keratinocytes studied by X-ray microanalysis, with special reference to contact dermatitis : In vivo and in vitro studies of functional changes in human cells
Sammanfattning : By determining the intracellular elemental content, information can be obtained on the physiological status of cells. The cellular content of sodium, magnesium, phosphorus, sulfur, chloride, potassium and calcium can be indicative for proliferation, cell membrane damage or cell death. LÄS MER
3. CCN2 – Keratinocyte Interactions In Vitro and In Vivo
Sammanfattning : Cutaneous wound healing is a complex process involving the migration of inflammatory cells to the wound site, deposition of extracellular matrix, and the reestablishment of an intact epithelial barrier. Re-epithelialization depends on the proliferation and directional migration of keratinocytes from the wound edges. LÄS MER
4. Treatment of Skin Wounds with Cell Transplantation and Gene Transfer
Sammanfattning : Background: A large number of different wound coverings have been used in order to improve the wound microenvironment, and thus accelerate repair. Since almost two centuries, clinicians and researchers have developed techniques for skin transplantation. LÄS MER
5. In vitro Studies of Genodermatoses Affecting Cytoskeletal Integrity and Lipid Processing in Human Epidermis : Pathogenic Mechanisms and Effects of Retinoid Therapy
Sammanfattning : Autosomal dominant epidermolytic ichthyosis (EI) is a rare disease characterized by intra-epidermal blistering due to mutations in either of two keratin genes, KRT1 and KRT10, expressed by suprabasal keratinocytes. Autosomal recessive congenital ichthyosis (ARCI) is a non-blistering, hyperkeratotic disease caused by mutations in one of the following genes: ABCA12, ALOX12B, ALOXE3, TGM1, CYP4F22, NIPAL4 and SLC27A4, which are all essential for skin barrier homeostasis. LÄS MER
