Sökning: "Natural killer NK cells"

Visar resultat 1 - 5 av 131 avhandlingar innehållade orden Natural killer NK cells.

  1. 1. The role of natural killer cells and inflammatory mediators in preeclamptic pregnancies

    Författare :Nora Bachmayer; Eva Sverremark-Ekström; Katarina Bremme; Lucia Mincheva-Nilsson; Stockholms universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; preeclampsia; NK cells; Immunology; Immunologi; immunologi; Immunology;

    Sammanfattning : The maternal immune system must be able to adjust during pregnancy and accept the foetus that expresses paternal antigens. These changes are found both in placenta and circulation, including a mild inflammatory response. NK cells are abundant during the early part of pregnancy in placenta and are thought to be important for placental development. LÄS MER

  2. 2. Dendritic cells in cancer immunotherapy

    Författare :Karin Gustafsson; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :vaccines; dendritic cells; αDC1; PGE2DC; natural killer cells; T cells;

    Sammanfattning : Dendritic cells (DCs) play a central role in the initiation and regulation of innate and adaptive immune responses and have increasingly been applied as vaccines for cancer patients. Ex vivo generation and antigen loading of monocyte-derived DCs allows a controlled maturation, with the aim of imprinting different DC functions that are essential for their subsequent induction of a T cell-mediated anti-tumor response. LÄS MER

  3. 3. The Role of Plasmacytoid Dendritic Cells and Natural Killer Cells in Systemic Lupus Erythematosus

    Författare :Niklas Hagberg; Lars Rönnblom; Maija-Leena Eloranta; George Tsokos; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Systemic lupus erythematosus; plasmacytoid dendritic cells; natural killer cells; type I interferon; immune complex; SLAM receptors; autoantibodies; CD94 NKG2A; CD94 NKG2C; Medicinsk vetenskap; Medical Science; Immunologi; Immunology;

    Sammanfattning : Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by autoantibody production, which can eventually lead to immune complex (IC)-mediated organ damage. Due to the stimulation of plasmacytoid dendritic cells (pDC) by nucleic acid-containing ICs (DNA- or RNA-IC), patients with SLE have an ongoing interferon (IFN)-α production. LÄS MER

  4. 4. The leukocyte complexity and mutational landscape of periampullary adenocarcinoma. Morphology matters

    Författare :Sebastian Lundgren; Tumörmikromiljö; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; periampullary adenocarcinoma; pancreatic cancer; immune microenviroment; prognosis; macrophages; natural killer cells; natural killer T cells; T cells; B cells;

    Sammanfattning : Background: Periampullary adenocarcinomas are a heterogenous group of tumours with poor prognosis that hasnot improved considerably the last decades. Tumour morphology, i.e. intestinal type (I-type) or pancreatobiliarytype (PB-type), has been demonstrated to be a more relevant prognostic factor than anatomical origin. LÄS MER

  5. 5. T Cells and NK Cells in Coronary Artery Disease : Longitudinal and methodological studies in humans

    Författare :Karin Backteman; Jan Ernerudh; Lena Jonasson; Joachim Lundahl; Linköpings universitet; []

    Sammanfattning : Coronary artery disease (CAD) is the leading cause of death worldwide and most often due to atherosclerosis. Atherosclerosis is a chronic inflammatory process that involves the arteries, inclouding those that supply blood to the heart muscle. LÄS MER